ENSG00000197361


Homo sapiens

Features
Gene ID: ENSG00000197361
  
Biological name :FBXL22
  
Synonyms : F-box and leucine rich repeat protein 22 / FBXL22 / Q6P050
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: 1
Band: q22.31
Gene start: 63597353
Gene end: 63602428
  
Corresponding Affymetrix probe sets: 241350_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000492359
Ensembl peptide - ENSP00000353794
Ensembl peptide - ENSP00000453697
Ensembl peptide - ENSP00000473666
NCBI entrez gene - 283807     See in Manteia.
OMIM - 609088
RefSeq - XM_011521469
RefSeq - NM_203373
RefSeq - XM_005254320
RefSeq - XM_011521468
RefSeq Peptide - NP_976307
swissprot - Q6P050
swissprot - R4GNI3
swissprot - H0YMQ4
swissprot - A0A1W2PQW8
Ensembl - ENSG00000197361
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxl22ENSDARG00000096995Danio rerio
 FBXL22ENSGALG00000003401Gallus gallus
 Fbxl22ENSMUSG00000050503Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR006553  Leucine-rich repeat, cysteine-containing subtype
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IDA
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0030018 Z disc IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IDA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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