ENSMUSG00000050503


Mus musculus

Features
Gene ID: ENSMUSG00000050503
  
Biological name :Fbxl22
  
Synonyms : F-box and leucine-rich protein 22 / Fbxl22 / Q8C7B6
  
Possible biological names infered from orthology : F-box and leucine rich repeat protein 22 / Q6P050
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: C
Gene start: 66508459
Gene end: 66514593
  
Corresponding Affymetrix probe sets: 10594609 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000060137
NCBI entrez gene - 74165     See in Manteia.
MGI - MGI:1921415
RefSeq - NM_175206
RefSeq Peptide - NP_780415
swissprot - Q8C7B6
Ensembl - ENSMUSG00000050503
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxl22ENSDARG00000096995Danio rerio
 FBXL22ENSGALG00000003401Gallus gallus
 FBXL22ENSG00000197361Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006553  Leucine-rich repeat, cysteine-containing subtype
 IPR032675  Leucine-rich repeat domain superfamily
 IPR036047  F-box-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IEA
 cellular_componentGO:0030018 Z disc IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity ISO


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Clrn1tm1.1(KOMP)Vlcg/Clrn1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Clrn1tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr