ENSG00000197580


Homo sapiens

Features
Gene ID: ENSG00000197580
  
Biological name :BCO2
  
Synonyms : BCO2 / beta-carotene oxygenase 2 / Q9BYV7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q23.1
Gene start: 112175467
Gene end: 112224699
  
Corresponding Affymetrix probe sets: 232449_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436615
Ensembl peptide - ENSP00000436956
Ensembl peptide - ENSP00000476560
Ensembl peptide - ENSP00000437053
Ensembl peptide - ENSP00000350314
Ensembl peptide - ENSP00000354338
Ensembl peptide - ENSP00000414843
Ensembl peptide - ENSP00000431802
Ensembl peptide - ENSP00000431882
Ensembl peptide - ENSP00000432045
Ensembl peptide - ENSP00000434488
Ensembl peptide - ENSP00000435869
NCBI entrez gene - 83875     See in Manteia.
OMIM - 611740
RefSeq - NM_001256397
RefSeq - NM_001256398
RefSeq - NM_001256400
RefSeq - NM_031938
RefSeq - NM_001037290
RefSeq Peptide - NP_001032367
RefSeq Peptide - NP_001243327
RefSeq Peptide - NP_001243329
RefSeq Peptide - NP_114144
RefSeq Peptide - NP_001243326
swissprot - V9GYA9
swissprot - E9PPP9
swissprot - H0YCL7
swissprot - H0YCN8
swissprot - Q9BYV7
swissprot - E9PS89
Ensembl - ENSG00000197580
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bco2aENSDARG00000055722Danio rerio
 bco2bENSDARG00000041715Danio rerio
 bco2lENSDARG00000027620Danio rerio
 BCO2ENSGALG00000007868Gallus gallus
 Bco2ENSMUSG00000032066Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
BCO1 / Q9HAY6 / beta-carotene oxygenase 1ENSG0000013569735
RPE65 / Q16518 / RPE65, retinoid isomerohydrolaseENSG0000011674534


Protein motifs (from Interpro)
Interpro ID Name
 IPR004294  Carotenoid oxygenase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001523 retinoid metabolic process TAS
 biological_processGO:0016116 carotenoid metabolic process ISS
 biological_processGO:0016119 carotene metabolic process IDA
 biological_processGO:0016121 carotene catabolic process IDA
 biological_processGO:0016122 xanthophyll metabolic process IEA
 biological_processGO:0042573 retinoic acid metabolic process NAS
 biological_processGO:0042574 retinal metabolic process NAS
 biological_processGO:0051881 regulation of mitochondrial membrane potential ISS
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:2000377 regulation of reactive oxygen species metabolic process ISS
 cellular_componentGO:0005622 intracellular IC
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005759 mitochondrial matrix TAS
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051213 dioxygenase activity IEA
 molecular_functionGO:0102076 beta,beta-carotene-9",10"-cleaving oxygenase activity IEA


Pathways (from Reactome)
Pathway description
Retinoid metabolism and transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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