ENSG00000197971


Homo sapiens

Features
Gene ID: ENSG00000197971
  
Biological name :MBP
  
Synonyms : MBP / myelin basic protein / P02686
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: -1
Band: q23
Gene start: 76978827
Gene end: 77133683
  
Corresponding Affymetrix probe sets: 1554544_a_at (Human Genome U133 Plus 2.0 Array)   207323_s_at (Human Genome U133 Plus 2.0 Array)   209072_at (Human Genome U133 Plus 2.0 Array)   210136_at (Human Genome U133 Plus 2.0 Array)   225407_at (Human Genome U133 Plus 2.0 Array)   225408_at (Human Genome U133 Plus 2.0 Array)   228938_at (Human Genome U133 Plus 2.0 Array)   236324_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000436830
Ensembl peptide - ENSP00000436951
Ensembl peptide - ENSP00000463780
Ensembl peptide - ENSP00000463403
Ensembl peptide - ENSP00000463164
Ensembl peptide - ENSP00000463137
Ensembl peptide - ENSP00000462780
Ensembl peptide - ENSP00000462758
Ensembl peptide - ENSP00000462734
Ensembl peptide - ENSP00000462374
Ensembl peptide - ENSP00000462223
Ensembl peptide - ENSP00000442393
Ensembl peptide - ENSP00000437063
Ensembl peptide - ENSP00000346545
Ensembl peptide - ENSP00000348273
Ensembl peptide - ENSP00000352667
Ensembl peptide - ENSP00000372025
Ensembl peptide - ENSP00000380958
Ensembl peptide - ENSP00000380961
Ensembl peptide - ENSP00000380963
Ensembl peptide - ENSP00000380964
Ensembl peptide - ENSP00000380967
Ensembl peptide - ENSP00000380973
Ensembl peptide - ENSP00000405882
Ensembl peptide - ENSP00000431267
Ensembl peptide - ENSP00000431335
Ensembl peptide - ENSP00000432988
Ensembl peptide - ENSP00000434011
Ensembl peptide - ENSP00000435243
Ensembl peptide - ENSP00000435322
Ensembl peptide - ENSP00000435641
NCBI entrez gene - 4155     See in Manteia.
OMIM - 159430
RefSeq - NM_001025090
RefSeq - NM_001025092
RefSeq - NM_001025100
RefSeq - NM_001025101
RefSeq - NM_002385
RefSeq - NM_001025081
RefSeq - XM_011526009
RefSeq - XM_017025778
RefSeq - XM_017025780
RefSeq Peptide - NP_001020272
RefSeq Peptide - NP_002376
RefSeq Peptide - NP_001020252
RefSeq Peptide - NP_001020261
RefSeq Peptide - NP_001020263
RefSeq Peptide - NP_001020271
swissprot - H7BYR8
swissprot - J3KS94
swissprot - J3KT01
swissprot - J3KT34
swissprot - E9PSE2
swissprot - J3QKN5
swissprot - J3QL64
swissprot - J3QQK6
swissprot - P02686
swissprot - J3QKL5
swissprot - E9PQE7
swissprot - E9PNZ1
swissprot - E9PMR5
swissprot - E9PLU9
swissprot - E9PLQ9
swissprot - E9PKX9
swissprot - E9PJ72
swissprot - C9J6H1
swissprot - A8MZH3
swissprot - A0A024R384
swissprot - F5H7N4
swissprot - F8WEU6
swissprot - H0YEA2
swissprot - H0YF02
Ensembl - ENSG00000197971
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mbpbENSDARG00000089413Danio rerio
 MBPENSGALG00000013640Gallus gallus
 MbpENSMUSG00000041607Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000548  Myelin basic protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IDA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0007417 central nervous system development TAS
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0008366 axon ensheathment TAS
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0021762 substantia nigra development HEP
 biological_processGO:0034115 negative regulation of heterotypic cell-cell adhesion IDA
 biological_processGO:0035633 maintenance of permeability of blood-brain barrier IDA
 biological_processGO:0042552 myelination IBA
 biological_processGO:0061024 membrane organization IEA
 biological_processGO:1904209 positive regulation of chemokine (C-C motif) ligand 2 secretion IDA
 biological_processGO:1904685 positive regulation of metalloendopeptidase activity IDA
 biological_processGO:2000778 positive regulation of interleukin-6 secretion IDA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0033269 internode region of axon IBA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043025 neuronal cell body IBA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0043218 compact myelin IBA
 cellular_componentGO:0071944 cell periphery IBA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding IPI
 molecular_functionGO:0019911 structural constituent of myelin sheath IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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