ENSG00000198060


Homo sapiens

Features
Gene ID: ENSG00000198060
  
Biological name :MARCH5
  
Synonyms : MARCH5 / membrane associated ring-CH-type finger 5 / Q9NX47
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q23.32
Gene start: 92291163
Gene end: 92353964
  
Corresponding Affymetrix probe sets: 218582_at (Human Genome U133 Plus 2.0 Array)   226394_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000351813
NCBI entrez gene - 54708     See in Manteia.
OMIM - 610637
RefSeq - NM_017824
RefSeq - XM_011539886
RefSeq Peptide - NP_060294
swissprot - Q9NX47
Ensembl - ENSG00000198060
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 march5ENSDARG00000032552Danio rerio
 MARCH5ENSGALG00000032234Gallus gallus
 March5ENSMUSG00000023307Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011016  Zinc finger, RING-CH-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR033275  E3 ubiquitin-protein ligase MARCH-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IDA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051865 protein autoubiquitination IDA
 biological_processGO:0070585 protein localization to mitochondrion IMP
 biological_processGO:0090140 regulation of mitochondrial fission IMP
 biological_processGO:0090141 positive regulation of mitochondrial fission IMP
 biological_processGO:0090344 negative regulation of cell aging IMP
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051020 GTPase binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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