ENSMUSG00000023307


Mus musculus

Features
Gene ID: ENSMUSG00000023307
  
Biological name :March5
  
Synonyms : E3 ubiquitin-protein ligase MARCH5 / March5 / Q3KNM2
  
Possible biological names infered from orthology : membrane associated ring-CH-type finger 5 / Q9NX47
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: C2
Gene start: 37207543
Gene end: 37222139
  
Corresponding Affymetrix probe sets: 10462791 (MoGene1.0st)   1428843_at (Mouse Genome 430 2.0 Array)   1429910_at (Mouse Genome 430 2.0 Array)   1430994_at (Mouse Genome 430 2.0 Array)   1452925_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000108010
Ensembl peptide - ENSMUSP00000118920
Ensembl peptide - ENSMUSP00000024078
NCBI entrez gene - 69104     See in Manteia.
MGI - MGI:1915207
RefSeq - XM_006527322
RefSeq - NM_001164336
RefSeq - NM_027314
RefSeq Peptide - NP_001157808
RefSeq Peptide - NP_081590
swissprot - Q3KNM2
swissprot - A2RTC8
swissprot - F6W8T3
swissprot - A0A0R4J1H0
Ensembl - ENSMUSG00000023307
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 march5ENSDARG00000032552Danio rerio
 MARCH5ENSGALG00000032234Gallus gallus
 MARCH5ENSG00000198060Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011016  Zinc finger, RING-CH-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR033275  E3 ubiquitin-protein ligase MARCH-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination ISO
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0051865 protein autoubiquitination ISO
 biological_processGO:0070585 protein localization to mitochondrion ISO
 biological_processGO:0090140 regulation of mitochondrial fission ISO
 biological_processGO:0090141 positive regulation of mitochondrial fission ISO
 biological_processGO:0090344 negative regulation of cell aging ISS
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005741 mitochondrial outer membrane ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051020 GTPase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Map2k2tm1a(EUCOMM)Wtsi/Map2k2tm1a(EUCOMM)Wtsi
Genetic Background: B6JTyr;B6N-Map2k2tm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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