ENSG00000204308


Homo sapiens

Features
Gene ID: ENSG00000204308
  
Biological name :RNF5
  
Synonyms : Q99942 / ring finger protein 5 / RNF5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.32
Gene start: 32178354
Gene end: 32180793
  
Corresponding Affymetrix probe sets: 209111_at (Human Genome U133 Plus 2.0 Array)   216018_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364235
NCBI entrez gene - 6048     See in Manteia.
OMIM - 602677
RefSeq - NM_006913
RefSeq Peptide - NP_008844
swissprot - A0A024RCQ4
swissprot - Q99942
Ensembl - ENSG00000204308
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RNF5ENSDARG00000075606Danio rerio
 Rnf5ENSMUSG00000015478Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009617 response to bacterium IEA
 biological_processGO:0010507 negative regulation of autophagy IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:0031648 protein destabilization IEA
 biological_processGO:0036503 ERAD pathway IMP
 biological_processGO:0044257 cellular protein catabolic process IMP
 biological_processGO:0055085 transmembrane transport TAS
 biological_processGO:0070534 protein K63-linked ubiquitination IDA
 biological_processGO:0070936 protein K48-linked ubiquitination IDA
 biological_processGO:0071712 ER-associated misfolded protein catabolic process IMP
 biological_processGO:1904380 endoplasmic reticulum mannose trimming TAS
 biological_processGO:2000785 regulation of autophagosome assembly IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0036513 Derlin-1 retrotranslocation complex IDA
 cellular_componentGO:0044322 endoplasmic reticulum quality control compartment IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0044390 ubiquitin-like protein conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport
Defective CFTR causes cystic fibrosis
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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