ENSMUSG00000015478


Mus musculus

Features
Gene ID: ENSMUSG00000015478
  
Biological name :Rnf5
  
Synonyms : E3 ubiquitin-protein ligase RNF5 / O35445 / Rnf5
  
Possible biological names infered from orthology : Q99942 / ring finger protein 5
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: B1
Gene start: 34601091
Gene end: 34603690
  
Corresponding Affymetrix probe sets: 10450206 (MoGene1.0st)   1422888_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000015622
NCBI entrez gene - 54197     See in Manteia.
MGI - MGI:1860076
RefSeq - NM_019403
RefSeq Peptide - NP_062276
swissprot - O35445
Ensembl - ENSMUSG00000015478
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 RNF5ENSDARG00000075606Danio rerio
 RNF5ENSG00000204308Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q91YT2 / Rnf185 / E3 ubiquitin-protein ligase RNF185 ENSMUSG0000002044862


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017907  Zinc finger, RING-type, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009617 response to bacterium IMP
 biological_processGO:0010507 negative regulation of autophagy IMP
 biological_processGO:0016567 protein ubiquitination IDA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IEA
 biological_processGO:0031648 protein destabilization IDA
 biological_processGO:0036503 ERAD pathway IEA
 biological_processGO:0044257 cellular protein catabolic process IEA
 biological_processGO:0070534 protein K63-linked ubiquitination IEA
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 biological_processGO:0071712 ER-associated misfolded protein catabolic process IEA
 biological_processGO:2000785 regulation of autophagosome assembly IMP
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0036513 Derlin-1 retrotranslocation complex IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0044390 ubiquitin-like protein conjugating enzyme binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
ABC-family proteins mediated transport
ER Quality Control Compartment (ERQC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000750 abnormal muscle regeneration "inability or defects in ability to repair muscle after injuries" [J:42574]
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Allelic Composition: Dtnbp1sdy-Btlr/Dtnbp1sdy-Btlr
Genetic Background: C57BL/6J-Dtnbp1sdy-Btlr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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