ENSG00000204397


Homo sapiens

Features
Gene ID: ENSG00000204397
  
Biological name :CARD16
  
Synonyms : CARD16 / caspase recruitment domain family member 16 / Q5EG05
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q22.3
Gene start: 105041326
Gene end: 105101431
  
Corresponding Affymetrix probe sets: 1552701_a_at (Human Genome U133 Plus 2.0 Array)   1552703_s_at (Human Genome U133 Plus 2.0 Array)   1554744_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364858
Ensembl peptide - ENSP00000433700
Ensembl peptide - ENSP00000432485
Ensembl peptide - ENSP00000364856
NCBI entrez gene - 114769     See in Manteia.
OMIM - 615680
RefSeq - XM_011542583
RefSeq - NM_001017534
RefSeq - NM_052889
RefSeq Peptide - NP_001017534
RefSeq Peptide - NP_443121
swissprot - Q5EG05
swissprot - E9PQW1
Ensembl - ENSG00000204397
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CARD17 / Q5XLA6 / caspase recruitment domain family member 17ENSG0000025522140
CARD18 / P57730 / caspase recruitment domain family member 18ENSG0000025550125


Protein motifs (from Interpro)
Interpro ID Name
 IPR001315  CARD domain
 IPR011029  Death-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway IMP
 biological_processGO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway IDA
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0050713 negative regulation of interleukin-1 beta secretion IDA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0071222 cellular response to lipopolysaccharide IDA
 biological_processGO:0071456 cellular response to hypoxia IDA
 biological_processGO:0071494 cellular response to UV-C IDA
 biological_processGO:0097340 inhibition of cysteine-type endopeptidase activity IDA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0097179 protease inhibitor complex IDA
 molecular_functionGO:0004869 cysteine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019900 kinase binding IPI
 molecular_functionGO:0030414 peptidase inhibitor activity IEA
 molecular_functionGO:0042802 identical protein binding IDA
 molecular_functionGO:0050700 CARD domain binding IPI
 molecular_functionGO:0089720 caspase binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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