ENSG00000255501


Homo sapiens

Features
Gene ID: ENSG00000255501
  
Biological name :CARD18
  
Synonyms : CARD18 / caspase recruitment domain family member 18 / P57730
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q22.3
Gene start: 105137721
Gene end: 105139726
  
Corresponding Affymetrix probe sets: 231733_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000437035
Ensembl peptide - ENSP00000437187
Ensembl peptide - ENSP00000436691
NCBI entrez gene - 59082     See in Manteia.
OMIM - 605354
RefSeq - NM_021571
RefSeq Peptide - NP_067546
swissprot - G5EA35
swissprot - P57730
Ensembl - ENSG00000255501
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CARD16 / Q5EG05 / caspase recruitment domain family member 16ENSG0000020439756
CARD17 / Q5XLA6 / caspase recruitment domain family member 17ENSG0000025522154


Protein motifs (from Interpro)
Interpro ID Name
 IPR001315  CARD domain
 IPR011029  Death-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006954 inflammatory response NAS
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0032091 negative regulation of protein binding IDA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0050713 negative regulation of interleukin-1 beta secretion IDA
 biological_processGO:0097194 execution phase of apoptosis IBA
 biological_processGO:0097340 inhibition of cysteine-type endopeptidase activity IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0032991 protein-containing complex IDA
 molecular_functionGO:0004869 cysteine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030414 peptidase inhibitor activity IEA
 molecular_functionGO:0050700 CARD domain binding IPI
 molecular_functionGO:0089720 caspase binding IPI
 molecular_functionGO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr