ENSG00000204463


Homo sapiens

Features
Gene ID: ENSG00000204463
  
Biological name :BAG6
  
Synonyms : BAG6 / BCL2 associated athanogene 6 / P46379
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.33
Gene start: 31639028
Gene end: 31652705
  
Corresponding Affymetrix probe sets: 201255_x_at (Human Genome U133 Plus 2.0 Array)   210208_x_at (Human Genome U133 Plus 2.0 Array)   213318_s_at (Human Genome U133 Plus 2.0 Array)   230513_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000413225
Ensembl peptide - ENSP00000411083
Ensembl peptide - ENSP00000413561
Ensembl peptide - ENSP00000416633
Ensembl peptide - ENSP00000211379
Ensembl peptide - ENSP00000354875
Ensembl peptide - ENSP00000365131
Ensembl peptide - ENSP00000365143
Ensembl peptide - ENSP00000388244
Ensembl peptide - ENSP00000391613
Ensembl peptide - ENSP00000391783
Ensembl peptide - ENSP00000394856
Ensembl peptide - ENSP00000396503
Ensembl peptide - ENSP00000397978
Ensembl peptide - ENSP00000401031
Ensembl peptide - ENSP00000402856
Ensembl peptide - ENSP00000404971
Ensembl peptide - ENSP00000406302
Ensembl peptide - ENSP00000406434
Ensembl peptide - ENSP00000406436
Ensembl peptide - ENSP00000410280
Ensembl peptide - ENSP00000411043
NCBI entrez gene - 7917     See in Manteia.
OMIM - 142590
RefSeq - XM_017011298
RefSeq - XM_017011275
RefSeq - XM_017011276
RefSeq - XM_017011277
RefSeq - XM_017011278
RefSeq - XM_017011279
RefSeq - XM_017011280
RefSeq - XM_017011281
RefSeq - XM_017011282
RefSeq - XM_017011283
RefSeq - XM_017011284
RefSeq - XM_017011285
RefSeq - XM_017011286
RefSeq - XM_017011287
RefSeq - XM_017011288
RefSeq - XM_017011289
RefSeq - XM_017011290
RefSeq - XM_017011291
RefSeq - XM_017011292
RefSeq - XM_017011293
RefSeq - XM_017011294
RefSeq - XM_017011295
RefSeq - XM_017011296
RefSeq - XM_017011297
RefSeq - NM_001098534
RefSeq - NM_001199697
RefSeq - NM_001199698
RefSeq - NM_004639
RefSeq - NM_080702
RefSeq - NM_080703
RefSeq - XM_011514892
RefSeq Peptide - NP_004630
RefSeq Peptide - NP_542433
RefSeq Peptide - NP_542434
RefSeq Peptide - NP_001092004
RefSeq Peptide - NP_001186626
RefSeq Peptide - NP_001186627
swissprot - F6VEM6
swissprot - F6WML8
swissprot - F6X9W3
swissprot - F6XTU0
swissprot - H0Y4L1
swissprot - A0A1U9X7A6
swissprot - H0Y759
swissprot - H0Y7K4
swissprot - P46379
swissprot - X6REW1
swissprot - A0A1B0GX79
swissprot - H0Y710
swissprot - F6S6P2
swissprot - F6TC96
swissprot - F6U1F2
swissprot - F6U341
swissprot - F6UR09
Ensembl - ENSG00000204463
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bag6ENSDARG00000075892Danio rerio
 bag6lENSDARG00000077531Danio rerio
 Bag6ENSMUSG00000024392Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000626  Ubiquitin domain
 IPR019954  Ubiquitin conserved site
 IPR021925  Large proline-rich protein BAG6
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001822 kidney development ISS
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002429 immune response-activating cell surface receptor signaling pathway IDA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process ISS
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007130 synaptonemal complex assembly ISS
 biological_processGO:0007283 spermatogenesis ISS
 biological_processGO:0007420 brain development ISS
 biological_processGO:0009790 embryo development ISS
 biological_processGO:0010498 proteasomal protein catabolic process IMP
 biological_processGO:0018393 internal peptidyl-lysine acetylation IDA
 biological_processGO:0030101 natural killer cell activation IDA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030324 lung development ISS
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway IMP
 biological_processGO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process ISS
 biological_processGO:0042127 regulation of cell proliferation IEA
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045861 negative regulation of proteolysis ISS
 biological_processGO:0050821 protein stabilization ISS
 biological_processGO:0061857 endoplasmic reticulum stress-induced pre-emptive quality control IMP
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ISS
 biological_processGO:0071712 ER-associated misfolded protein catabolic process IDA
 biological_processGO:0071816 tail-anchored membrane protein insertion into ER membrane IDA
 biological_processGO:1904294 positive regulation of ERAD pathway IMP
 biological_processGO:1904378 maintenance of unfolded protein involved in ERAD pathway IMP
 biological_processGO:1904379 protein localization to cytosolic proteasome complex involved in ERAD pathway NAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome IEA
 cellular_componentGO:0071818 BAT3 complex IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030544 Hsp70 protein binding IEA
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding ISS
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0043022 ribosome binding IDA
 molecular_functionGO:0051787 misfolded protein binding IDA
 molecular_functionGO:0070628 proteasome binding ISS
 molecular_functionGO:1990381 ubiquitin-specific protease binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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