ENSG00000204472


Homo sapiens

Features
Gene ID: ENSG00000204472
  
Biological name :AIF1
  
Synonyms : AIF1 / allograft inflammatory factor 1 / P55008
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.33
Gene start: 31615184
Gene end: 31617021
  
Corresponding Affymetrix probe sets: 207823_s_at (Human Genome U133 Plus 2.0 Array)   209901_x_at (Human Genome U133 Plus 2.0 Array)   213095_x_at (Human Genome U133 Plus 2.0 Array)   215051_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000338776
Ensembl peptide - ENSP00000365217
Ensembl peptide - ENSP00000365227
NCBI entrez gene - 199     See in Manteia.
OMIM - 601833
RefSeq - XM_017010332
RefSeq - NM_001318970
RefSeq - NM_001623
RefSeq - NM_032955
RefSeq - XM_005248870
RefSeq Peptide - NP_116573
RefSeq Peptide - NP_001614
RefSeq Peptide - NP_001305899
swissprot - I3WTX1
swissprot - Q4V347
swissprot - P55008
swissprot - Q5STX8
Ensembl - ENSG00000204472
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Aif1ENSMUSG00000024397Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AIF1L / Q9BQI0 / allograft inflammatory factor 1 likeENSG0000012687863


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001774 microglial cell activation NAS
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006911 phagocytosis, engulfment ISS
 biological_processGO:0006954 inflammatory response NAS
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0014739 positive regulation of muscle hyperplasia IEA
 biological_processGO:0016601 Rac protein signal transduction ISS
 biological_processGO:0030041 actin filament polymerization IDA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0031668 cellular response to extracellular stimulus IEA
 biological_processGO:0032870 cellular response to hormone stimulus IEA
 biological_processGO:0034097 response to cytokine IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IDA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IDA
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IDA
 biological_processGO:0048678 response to axon injury IEA
 biological_processGO:0051017 actin filament bundle assembly IDA
 biological_processGO:0051384 response to glucocorticoid IEA
 biological_processGO:0051602 response to electrical stimulus IEA
 biological_processGO:0071315 cellular response to morphine IEA
 biological_processGO:0071346 cellular response to interferon-gamma ISS
 biological_processGO:0071447 cellular response to hydroperoxide IEA
 biological_processGO:0071672 negative regulation of smooth muscle cell chemotaxis IDA
 biological_processGO:0071673 positive regulation of smooth muscle cell chemotaxis IDA
 biological_processGO:0090026 positive regulation of monocyte chemotaxis IDA
 biological_processGO:0097178 ruffle assembly NAS
 biological_processGO:1900087 positive regulation of G1/S transition of mitotic cell cycle IDA
 biological_processGO:2000406 positive regulation of T cell migration IDA
 cellular_componentGO:0001726 ruffle IEA
 cellular_componentGO:0001891 phagocytic cup ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005884 actin filament IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030027 lamellipodium ISS
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005509 calcium ion binding ISS
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr