ENSG00000204815


Homo sapiens

Features
Gene ID: ENSG00000204815
  
Biological name :TTC25
  
Synonyms : Q96NG3 / tetratricopeptide repeat domain 25 / TTC25
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q21.2
Gene start: 41930635
Gene end: 41965651
  
Corresponding Affymetrix probe sets: 223924_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000477931
Ensembl peptide - ENSP00000484975
Ensembl peptide - ENSP00000479460
Ensembl peptide - ENSP00000478589
NCBI entrez gene - 83538     See in Manteia.
OMIM - 617095
RefSeq - NM_031421
RefSeq - XM_011525324
RefSeq - XM_011525323
RefSeq Peptide - NP_113609
swissprot - A0A087X2G9
swissprot - Q96NG3
swissprot - A0A087WTJ8
swissprot - A0A087WVI5
Ensembl - ENSG00000204815
  
Related genetic diseases (OMIM): 617092 - Ciliary dyskinesia, primary, 35, 617092
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ttc25ENSDARG00000058140Danio rerio
 TTC25ENSGALG00000003464Gallus gallus
 Ttc25ENSMUSG00000006784Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 HP:0000007 Autosomal recessive inheritance "A mode of inheritance that is observed for traits related to a gene encoded on one of the autosomes (i.e., the human chromosomes 1-22) in which a trait manifests in homozygotes. In the context of medical genetics, autosomal recessive disorders manifest in homozygotes (with two copies of the mutant allele) or compound heterozygotes (whereby each copy of a gene has a distinct mutant allele)." [HPO:curators]
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 HP:0001696 Situs inversus "A left-right reversal (or "mirror reflection") of the anatomical location of the major thoracic and abdominal organs." [HPO:curators]
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 HP:0002110 Bronchiectasis 
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 HP:0002205 Recurrent respiratory infections 
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 HP:0002257 Chronic rhinitis 
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 HP:0003577 Onset at birth 
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 HP:0011109 Chronic sinusitis "A chronic form of `sinusitis` (HP:0000246)." [HPO:probinson]
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 HP:0100582 Nasal polyposis "Polypoidal masses arising mainly from the mucous membranes of the nose and paranasal sinuses. They are freely movable and nontender overgrowths of the mucosa that frequently accompany allergic rhinitis." [HPO:sdoelken]
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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