ENSG00000204936


Homo sapiens

Features
Gene ID: ENSG00000204936
  
Biological name :CD177
  
Synonyms : CD177 / CD177 molecule / Q8N6Q3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.31
Gene start: 43353659
Gene end: 43363172
  
Corresponding Affymetrix probe sets: 219669_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000367251
Ensembl peptide - ENSP00000483817
Ensembl peptide - ENSP00000479536
NCBI entrez gene - 57126     See in Manteia.
OMIM - 162860
RefSeq - XM_017027021
RefSeq - XM_017027022
RefSeq - NM_020406
RefSeq Peptide - NP_065139
swissprot - Q8N6Q3
swissprot - A0A087X113
swissprot - A0A087WVM2
Ensembl - ENSG00000204936
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Cd177ENSMUSG00000052212Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9BY14 / TEX101 / testis expressed 101ENSG0000013112616
LYPD4 / Q6UWN0 / LY6/PLAUR domain containing 4ENSG0000027311114


Protein motifs (from Interpro)
Interpro ID Name
 IPR016054  Ly-6 antigen/uPA receptor-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0007155 cell adhesion IMP
 biological_processGO:0007159 leukocyte cell-cell adhesion IMP
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0030100 regulation of endocytosis IDA
 biological_processGO:0032930 positive regulation of superoxide anion generation IGI
 biological_processGO:0034394 protein localization to cell surface IMP
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043315 positive regulation of neutrophil degranulation IGI
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045217 cell-cell junction maintenance IMP
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0072672 neutrophil extravasation IMP
 biological_processGO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules IMP
 biological_processGO:1990266 neutrophil migration IMP
 biological_processGO:2001044 regulation of integrin-mediated signaling pathway IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030667 secretory granule membrane IDA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0044853 plasma membrane raft IDA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0070821 tertiary granule membrane IDA
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0005178 integrin binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0048306 calcium-dependent protein binding IPI


Pathways (from Reactome)
Pathway description
Common Pathway of Fibrin Clot Formation
Cell surface interactions at the vascular wall
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000196415 PRTN3 / P24158 / proteinase 3  / complex
 ENSG00000101000 PROCR / Q9UNN8 / protein C receptor  / reaction / complex






 

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