ENSG00000101000


Homo sapiens

Features
Gene ID: ENSG00000101000
  
Biological name :PROCR
  
Synonyms : PROCR / protein C receptor / Q9UNN8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: 1
Band: q11.22
Gene start: 35172073
Gene end: 35216240
  
Corresponding Affymetrix probe sets: 203650_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000216968
Ensembl peptide - ENSP00000489456
Ensembl peptide - ENSP00000489117
NCBI entrez gene - 10544     See in Manteia.
OMIM - 600646
RefSeq - NM_006404
RefSeq Peptide - NP_006395
swissprot - A0A0U1RRC4
swissprot - A0A0U1RQQ4
swissprot - Q9UNN8
Ensembl - ENSG00000101000
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PROCRENSGALG00000006547Gallus gallus
 ProcrENSMUSG00000027611Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011161  MHC class I-like antigen recognition-like
 IPR011162  MHC classes I/II-like antigen recognition protein
 IPR015669  Endothelial protein C receptor
 IPR037055  MHC class I-like antigen recognition-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0007599 hemostasis IEA
 biological_processGO:0050819 negative regulation of coagulation IMP
 biological_processGO:0050900 leukocyte migration TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0009986 cell surface HDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Common Pathway of Fibrin Clot Formation
Cell surface interactions at the vascular wall


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000115718 PROC / P04070 / protein C, inactivator of coagulation factors Va and VIIIa  / reaction / complex
 ENSG00000196415 PRTN3 / P24158 / proteinase 3  / complex / reaction
 ENSG00000180210 F2 / P00734 / coagulation factor II, thrombin  / reaction
 ENSG00000181104 F2R / P25116 / coagulation factor II thrombin receptor  / reaction / complex
 ENSG00000204936 CD177 / Q8N6Q3 / CD177 molecule  / reaction / complex






 

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