ENSG00000204991


Homo sapiens

Features
Gene ID: ENSG00000204991
  
Biological name :SPIRE2
  
Synonyms : Q8WWL2 / SPIRE2 / spire type actin nucleation factor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q24.3
Gene start: 89818179
Gene end: 89871319
  
Corresponding Affymetrix probe sets: 1568916_at (Human Genome U133 Plus 2.0 Array)   1569723_a_at (Human Genome U133 Plus 2.0 Array)   227706_at (Human Genome U133 Plus 2.0 Array)   243594_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000367494
Ensembl peptide - ENSP00000376782
Ensembl peptide - ENSP00000457940
Ensembl peptide - ENSP00000457981
NCBI entrez gene - 84501     See in Manteia.
OMIM - 609217
RefSeq - XM_017023781
RefSeq - XM_011523381
RefSeq - XM_011523384
RefSeq - XM_017023779
RefSeq - XM_017023780
RefSeq - NM_032451
RefSeq - XM_011523379
RefSeq - XM_011523380
RefSeq Peptide - NP_115827
swissprot - H3BV74
swissprot - H3BV39
swissprot - Q8WWL2
Ensembl - ENSG00000204991
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spire2ENSDARG00000003084Danio rerio
 SPIRE2ENSGALG00000000521Gallus gallus
 2 ENSMUSG00000010154Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q08AE8 / SPIRE1 / spire type actin nucleation factor 1ENSG0000013427840


Protein motifs (from Interpro)
Interpro ID Name
 IPR003124  WH2 domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011019  KIND domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR029901  Protein Spire
 IPR029904  Protein Spire2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0030036 actin cytoskeleton organization IEA
 biological_processGO:0036089 cleavage furrow formation IEA
 biological_processGO:0040038 polar body extrusion after meiotic divisions IEA
 biological_processGO:0045010 actin nucleation IEA
 biological_processGO:0046907 intracellular transport IEA
 biological_processGO:0051295 establishment of meiotic spindle localization IEA
 biological_processGO:0070649 formin-nucleated actin cable assembly IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005938 cell cortex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane ISS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0032154 cleavage furrow IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003779 actin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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