ENSG00000134278


Homo sapiens

Features
Gene ID: ENSG00000134278
  
Biological name :SPIRE1
  
Synonyms : Q08AE8 / SPIRE1 / spire type actin nucleation factor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: -1
Band: p11.21
Gene start: 12446512
Gene end: 12658134
  
Corresponding Affymetrix probe sets: 1554807_a_at (Human Genome U133 Plus 2.0 Array)   1559517_a_at (Human Genome U133 Plus 2.0 Array)   224995_at (Human Genome U133 Plus 2.0 Array)   225018_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467103
Ensembl peptide - ENSP00000466531
Ensembl peptide - ENSP00000467943
Ensembl peptide - ENSP00000309661
Ensembl peptide - ENSP00000387226
Ensembl peptide - ENSP00000387266
Ensembl peptide - ENSP00000401392
Ensembl peptide - ENSP00000404752
Ensembl peptide - ENSP00000407050
NCBI entrez gene - 56907     See in Manteia.
OMIM - 609216
RefSeq - XM_011525702
RefSeq - NM_001128626
RefSeq - NM_001128627
RefSeq - NM_020148
RefSeq - XM_005258122
RefSeq - XM_011525701
RefSeq Peptide - NP_001122098
RefSeq Peptide - NP_001122099
RefSeq Peptide - NP_064533
swissprot - K7EMJ7
swissprot - K7ENV1
swissprot - K7EQR2
swissprot - J3KNG6
swissprot - C9JYR7
swissprot - Q08AE8
Ensembl - ENSG00000134278
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q1LYM3ENSDARG00000035868Danio rerio
 spire1bENSDARG00000038445Danio rerio
 ENSGALG00000034052Gallus gallus
 ENSGALG00000013817Gallus gallus
 1 ENSMUSG00000024533Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q8WWL2 / SPIRE2 / spire type actin nucleation factor 2ENSG0000020499138


Protein motifs (from Interpro)
Interpro ID Name
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011019  KIND domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR029901  Protein Spire
 IPR029905  Protein Spire1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016192 vesicle-mediated transport IEA
 biological_processGO:0030036 actin cytoskeleton organization IMP
 biological_processGO:0036089 cleavage furrow formation ISS
 biological_processGO:0040038 polar body extrusion after meiotic divisions ISS
 biological_processGO:0045010 actin nucleation IEA
 biological_processGO:0046907 intracellular transport ISS
 biological_processGO:0051295 establishment of meiotic spindle localization IMP
 biological_processGO:0070649 formin-nucleated actin cable assembly ISS
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005938 cell cortex ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane ISS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0032154 cleavage furrow ISS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003779 actin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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