ENSG00000205669


Homo sapiens

Features
Gene ID: ENSG00000205669
  
Biological name :ACOT6
  
Synonyms : ACOT6 / acyl-CoA thioesterase 6 / Q3I5F7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q24.3
Gene start: 73610945
Gene end: 73619888
  
Corresponding Affymetrix probe sets: 241949_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370531
Ensembl peptide - ENSP00000451464
Ensembl peptide - ENSP00000496277
NCBI entrez gene - 641372     See in Manteia.
OMIM - 614267
RefSeq - XM_011537076
RefSeq - NM_001037162
RefSeq Peptide - NP_001032239
swissprot - Q3I5F7
swissprot - G3V3W6
Ensembl - ENSG00000205669
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acot20ENSDARG00000042510Danio rerio
 acot21ENSDARG00000042513Danio rerio
 acot22ENSDARG00000058945Danio rerio
 ENSGALG00000009292Gallus gallus
 Acot6ENSMUSG00000043487Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACOT2 / P49753 / acyl-CoA thioesterase 2ENSG0000011967358
ACOT1 / Q86TX2 / acyl-CoA thioesterase 1ENSG0000018422757
ACOT4 / Q8N9L9 / acyl-CoA thioesterase 4ENSG0000017746554
BAAT / Q14032 / bile acid-CoA:amino acid N-acyltransferaseENSG0000013688135


Protein motifs (from Interpro)
Interpro ID Name
 IPR006862  Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
 IPR014940  BAAT/Acyl-CoA thioester hydrolase C-terminal
 IPR016662  Acyl-CoA thioesterase, long chain
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006631 fatty acid metabolic process IBA
 biological_processGO:0006637 acyl-CoA metabolic process IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005782 peroxisomal matrix TAS
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016790 thiolester hydrolase activity IEA
 molecular_functionGO:0047617 acyl-CoA hydrolase activity IBA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Beta-oxidation of very long chain fatty acids


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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