ENSG00000119673


Homo sapiens

Features
Gene ID: ENSG00000119673
  
Biological name :ACOT2
  
Synonyms : ACOT2 / acyl-CoA thioesterase 2 / P49753
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q24.3
Gene start: 73567620
Gene end: 73575658
  
Corresponding Affymetrix probe sets: 202982_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000238651
Ensembl peptide - ENSP00000483704
Ensembl peptide - ENSP00000477685
Ensembl peptide - ENSP00000440961
NCBI entrez gene - 10965     See in Manteia.
OMIM - 609972
RefSeq - XM_006720007
RefSeq - NM_006821
RefSeq Peptide - NP_006812
swissprot - F6VI00
swissprot - A0A087X0W7
swissprot - P49753
swissprot - A0A087WT95
Ensembl - ENSG00000119673
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acot20ENSDARG00000042510Danio rerio
 acot21ENSDARG00000042513Danio rerio
 acot22ENSDARG00000058945Danio rerio
 ENSGALG00000009292Gallus gallus
 AC133183.1ENSMUSG00000113475Mus musculus
 Acot1ENSMUSG00000072949Mus musculus
 Acot2ENSMUSG00000021226Mus musculus
 Acot3ENSMUSG00000021228Mus musculus
 Acot5ENSMUSG00000042540Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ACOT1 / Q86TX2 / acyl-CoA thioesterase 1ENSG0000018422786
ACOT4 / Q8N9L9 / acyl-CoA thioesterase 4ENSG0000017746561
BAAT / Q14032 / bile acid-CoA:amino acid N-acyltransferaseENSG0000013688139
ACOT6 / Q3I5F7 / acyl-CoA thioesterase 6ENSG0000020566925


Protein motifs (from Interpro)
Interpro ID Name
 IPR006862  Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
 IPR014940  BAAT/Acyl-CoA thioester hydrolase C-terminal
 IPR016662  Acyl-CoA thioesterase, long chain
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000038 very long-chain fatty acid metabolic process IDA
 biological_processGO:0001676 long-chain fatty acid metabolic process IDA
 biological_processGO:0006637 acyl-CoA metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016290 palmitoyl-CoA hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016790 thiolester hydrolase activity IEA
 molecular_functionGO:0047617 acyl-CoA hydrolase activity IDA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA
 molecular_functionGO:0102991 myristoyl-CoA hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial Fatty Acid Beta-Oxidation
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr