ENSMUSG00000021226


Mus musculus

Features
Gene ID: ENSMUSG00000021226
  
Biological name :Acot2
  
Synonyms : Acot2 / acyl-CoA thioesterase 2 / Q9QYR9
  
Possible biological names infered from orthology : ACOT1 / acyl-CoA thioesterase 1 / P49753 / Q86TX2
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: D1
Gene start: 83987861
Gene end: 83993873
  
Corresponding Affymetrix probe sets: 10397145 (MoGene1.0st)   1422996_at (Mouse Genome 430 2.0 Array)   1422997_s_at (Mouse Genome 430 2.0 Array)   1439478_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000021649
NCBI entrez gene - 171210     See in Manteia.
MGI - MGI:2159605
RefSeq - NM_134188
RefSeq Peptide - NP_598949
swissprot - Q9QYR9
Ensembl - ENSMUSG00000021226
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acot20ENSDARG00000042510Danio rerio
 acot21ENSDARG00000042513Danio rerio
 acot22ENSDARG00000058945Danio rerio
 ENSGALG00000009292Gallus gallus
 ACOT1ENSG00000184227Homo sapiens
 ACOT2ENSG00000119673Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acot1 / O55137 / acyl-CoA thioesterase 1 / ACOT2* / P49753* / Q86TX2* / acyl-CoA thioesterase 2*ENSMUSG0000007294985
Acot5 / Q6Q2Z6 / acyl-CoA thioesterase 5 / ACOT1* / ACOT2* / P49753* / Q86TX2* / acyl-CoA thioesterase 2* / acyl-CoA thioesterase 1*ENSMUSG0000004254070
Acot3 / Q9QYR7 / acyl-CoA thioesterase 3 / ACOT1* / ACOT2* / P49753* / Q86TX2* / acyl-CoA thioesterase 2* / acyl-CoA thioesterase 1*ENSMUSG0000002122870
Acot4 / Q8BWN8 / acyl-CoA thioesterase 4 / Q8N9L9*ENSMUSG0000005239260
Acot6 / Q32Q92 / Acyl-coenzyme A thioesterase 6 / Q3I5F7* / acyl-CoA thioesterase 6*ENSMUSG0000004348760
Baat / Q91X34 / Bile acid-CoA:amino acid N-acyltransferase / Q14032*ENSMUSG0000003965340
A2AKK5 / Acnat1 / acyl-coenzyme A amino acid N-acyltransferase 1ENSMUSG0000007098538
Acnat2 / Q8BGG9 / acyl-coenzyme A amino acid N-acyltransferase 2ENSMUSG0000006031737
AC133183.1 / ACOT1* / ACOT2* / Q86TX2* / P49753* / acyl-CoA thioesterase 1* / acyl-CoA thioesterase 2*ENSMUSG0000011347523


Protein motifs (from Interpro)
Interpro ID Name
 IPR006862  Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
 IPR014940  BAAT/Acyl-CoA thioester hydrolase C-terminal
 IPR016662  Acyl-CoA thioesterase, long chain
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000038 very long-chain fatty acid metabolic process ISO
 biological_processGO:0001676 long-chain fatty acid metabolic process ISO
 biological_processGO:0006631 fatty acid metabolic process IBA
 biological_processGO:0006637 acyl-CoA metabolic process TAS
 cellular_componentGO:0005739 mitochondrion TAS
 cellular_componentGO:0005759 mitochondrial matrix IEA
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0016290 palmitoyl-CoA hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016790 thiolester hydrolase activity IEA
 molecular_functionGO:0047617 acyl-CoA hydrolase activity TAS
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA
 molecular_functionGO:0102991 myristoyl-CoA hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Mitochondrial Fatty Acid Beta-Oxidation
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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