ENSMUSG00000052392


Mus musculus

Features
Gene ID: ENSMUSG00000052392
  
Biological name :Acot4
  
Synonyms : Acot4 / acyl-CoA thioesterase 4 / Q8BWN8
  
Possible biological names infered from orthology : Q8N9L9
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: D1
Gene start: 84038379
Gene end: 84048601
  
Corresponding Affymetrix probe sets: 10397153 (MoGene1.0st)   1422076_at (Mouse Genome 430 2.0 Array)   1422077_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000152805
Ensembl peptide - ENSMUSP00000021652
NCBI entrez gene - 171282     See in Manteia.
MGI - MGI:2159621
RefSeq - NM_134247
RefSeq Peptide - NP_599008
swissprot - A0A1Y7VK62
swissprot - Q14DI6
swissprot - Q8BWN8
Ensembl - ENSMUSG00000052392
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 acot20ENSDARG00000042510Danio rerio
 acot21ENSDARG00000042513Danio rerio
 acot22ENSDARG00000058945Danio rerio
 ENSGALG00000009292Gallus gallus
 ACOT4ENSG00000177465Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Acot6 / Q32Q92 / Acyl-coenzyme A thioesterase 6 / Q3I5F7* / acyl-CoA thioesterase 6*ENSMUSG0000004348768
Acot1 / O55137 / acyl-CoA thioesterase 1 / ACOT2* / P49753* / Q86TX2* / acyl-CoA thioesterase 2*ENSMUSG0000007294966
Acot5 / Q6Q2Z6 / acyl-CoA thioesterase 5 / ACOT1* / ACOT2* / P49753* / Q86TX2* / acyl-CoA thioesterase 2* / acyl-CoA thioesterase 1*ENSMUSG0000004254066
Acot2 / Q9QYR9 / acyl-CoA thioesterase 2 / ACOT1* / P49753* / Q86TX2* / acyl-CoA thioesterase 1*ENSMUSG0000002122665
Acot3 / Q9QYR7 / acyl-CoA thioesterase 3 / ACOT1* / ACOT2* / P49753* / Q86TX2* / acyl-CoA thioesterase 2* / acyl-CoA thioesterase 1*ENSMUSG0000002122865
Baat / Q91X34 / Bile acid-CoA:amino acid N-acyltransferase / Q14032*ENSMUSG0000003965342
Acnat2 / Q8BGG9 / acyl-coenzyme A amino acid N-acyltransferase 2ENSMUSG0000006031741
A2AKK5 / Acnat1 / acyl-coenzyme A amino acid N-acyltransferase 1ENSMUSG0000007098541
AC133183.1 / ACOT1* / ACOT2* / Q86TX2* / P49753* / acyl-CoA thioesterase 1* / acyl-CoA thioesterase 2*ENSMUSG0000011347519


Protein motifs (from Interpro)
Interpro ID Name
 IPR006862  Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase
 IPR014940  BAAT/Acyl-CoA thioester hydrolase C-terminal
 IPR016662  Acyl-CoA thioesterase, long chain
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000038 very long-chain fatty acid metabolic process IEA
 biological_processGO:0001676 long-chain fatty acid metabolic process IEA
 biological_processGO:0006104 succinyl-CoA metabolic process IDA
 biological_processGO:0006637 acyl-CoA metabolic process IDA
 biological_processGO:0032788 saturated monocarboxylic acid metabolic process ISO
 biological_processGO:0032789 unsaturated monocarboxylic acid metabolic process ISO
 biological_processGO:0043648 dicarboxylic acid metabolic process IDA
 biological_processGO:0043649 dicarboxylic acid catabolic process IEA
 biological_processGO:0046459 short-chain fatty acid metabolic process IDA
 cellular_componentGO:0005777 peroxisome TAS
 molecular_functionGO:0004778 succinyl-CoA hydrolase activity ISO
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0016290 palmitoyl-CoA hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016790 thiolester hydrolase activity IEA
 molecular_functionGO:0047617 acyl-CoA hydrolase activity IDA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA
 molecular_functionGO:0102991 myristoyl-CoA hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Beta-oxidation of very long chain fatty acids
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002059 abnormal seminal gland morphology "anomalous structure of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: A830005F24Riktm1.1(KOMP)Mbp/A830005F24Rik+
Genetic Background: C57BL/6N-A830005F24Riktm1.1(KOMP)Mbp/Ucd

 MP:0002135 abnormal kidney morphology "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: A830005F24Riktm1.1(KOMP)Mbp/A830005F24Rik+
Genetic Background: C57BL/6N-A830005F24Riktm1.1(KOMP)Mbp/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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