ENSG00000213088


Homo sapiens

Features
Gene ID: ENSG00000213088
  
Biological name :ACKR1
  
Synonyms : ACKR1 / atypical chemokine receptor 1 (Duffy blood group) / Q16570
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: q23.2
Gene start: 159203307
Gene end: 159206500
  
Corresponding Affymetrix probe sets: 208335_s_at (Human Genome U133 Plus 2.0 Array)   226953_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000357103
Ensembl peptide - ENSP00000357104
Ensembl peptide - ENSP00000398406
Ensembl peptide - ENSP00000441985
NCBI entrez gene - 2532     See in Manteia.
OMIM - 613665
RefSeq - NM_002036
RefSeq - NM_001122951
RefSeq Peptide - NP_001116423
RefSeq Peptide - NP_002027
swissprot - Q16570
swissprot - Q5JY94
swissprot - Q5Y7A1
swissprot - Q5Y7A2
Ensembl - ENSG00000213088
  
Related genetic diseases (OMIM): 110700 - [Blood group, Duffy system], 110700
  611162 - {Malaria, vivax, protection against}, 611162
  611862 - [White blood cell count QTL], 611862
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ackr1ENSMUSG00000037872Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005384  Duffy antigen/chemokine receptor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006952 defense response NAS
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0032642 regulation of chemokine production IBA
 biological_processGO:0070098 chemokine-mediated signaling pathway IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0055037 recycling endosome IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0019956 chemokine binding IEA
 molecular_functionGO:0019957 C-C chemokine binding IPI


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000169429 CXCL8 / P10145 / C-X-C motif chemokine ligand 8  / complex / reaction






 

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