ENSG00000213722


Homo sapiens

Features
Gene ID: ENSG00000213722
  
Biological name :DDAH2
  
Synonyms : DDAH2 / dimethylarginine dimethylaminohydrolase 2 / O95865
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: p21.33
Gene start: 31727038
Gene end: 31730617
  
Corresponding Affymetrix probe sets: 202262_x_at (Human Genome U133 Plus 2.0 Array)   214909_s_at (Human Genome U133 Plus 2.0 Array)   215537_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000413164
Ensembl peptide - ENSP00000395759
Ensembl peptide - ENSP00000397466
Ensembl peptide - ENSP00000364943
Ensembl peptide - ENSP00000364945
Ensembl peptide - ENSP00000364949
NCBI entrez gene - 23564     See in Manteia.
OMIM - 604744
RefSeq - XM_011514448
RefSeq - NM_001303007
RefSeq - NM_001303008
RefSeq - NM_013974
RefSeq Peptide - NP_001289936
RefSeq Peptide - NP_001289937
RefSeq Peptide - NP_039268
swissprot - O95865
swissprot - Q5SRR8
swissprot - Q5SSV3
swissprot - V9HW53
swissprot - H0Y7N1
Ensembl - ENSG00000213722
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ddah2ENSDARG00000105009Danio rerio
 Ddah2ENSMUSG00000007039Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDAH1 / O94760 / dimethylarginine dimethylaminohydrolase 1ENSG0000015390449


Protein motifs (from Interpro)
Interpro ID Name
 IPR033199  Dimethylarginine dimethylaminohydrolase/arginine deiminase
 IPR033202  N(G),N(G)-dimethylarginine dimethylaminohydrolase 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000052 citrulline metabolic process IEA
 biological_processGO:0006525 arginine metabolic process IEA
 biological_processGO:0006527 arginine catabolic process IEA
 biological_processGO:0006809 nitric oxide biosynthetic process TAS
 biological_processGO:0007263 nitric oxide mediated signal transduction TAS
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IEA
 biological_processGO:0050999 regulation of nitric-oxide synthase activity TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005815 microtubule organizing center IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003824 catalytic activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016403 dimethylargininase activity IEA
 molecular_functionGO:0016597 amino acid binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
eNOS activation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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