ENSG00000214517


Homo sapiens

Features
Gene ID: ENSG00000214517
  
Biological name :PPME1
  
Synonyms : PPME1 / protein phosphatase methylesterase 1 / Q9Y570
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.4
Gene start: 74171099
Gene end: 74254703
  
Corresponding Affymetrix probe sets: 217841_s_at (Human Genome U133 Plus 2.0 Array)   49077_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000381461
Ensembl peptide - ENSP00000329867
NCBI entrez gene - 51400     See in Manteia.
OMIM - 611117
RefSeq - NM_001271593
RefSeq - NM_016147
RefSeq Peptide - NP_001258522
RefSeq Peptide - NP_057231
swissprot - Q9Y570
swissprot - A0A140VK39
Ensembl - ENSG00000214517
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppme1ENSDARG00000009771Danio rerio
 PPME1ENSGALG00000017312Gallus gallus
 Ppme1ENSMUSG00000030718Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000073  Alpha/beta hydrolase fold-1
 IPR016812  Protein phosphatase methylesterase, eukaryotic
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0006482 protein demethylation IDA
 biological_processGO:0032515 negative regulation of phosphoprotein phosphatase activity IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0004864 protein phosphatase inhibitor activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity TAS
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019903 protein phosphatase binding IDA
 molecular_functionGO:0045296 cadherin binding IDA
 molecular_functionGO:0051721 protein phosphatase 2A binding IDA
 molecular_functionGO:0051722 protein C-terminal methylesterase activity TAS
 molecular_functionGO:0051723 protein methylesterase activity IEA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Cyclin A/B1/B2 associated events during G2/M transition


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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