ENSMUSG00000030718


Mus musculus

Features
Gene ID: ENSMUSG00000030718
  
Biological name :Ppme1
  
Synonyms : Ppme1 / Protein phosphatase methylesterase 1 / Q8BVQ5
  
Possible biological names infered from orthology : Q9Y570
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: E2
Gene start: 100326737
Gene end: 100372307
  
Corresponding Affymetrix probe sets: 10565873 (MoGene1.0st)   1423810_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000146716
Ensembl peptide - ENSMUSP00000032963
NCBI entrez gene - 72590     See in Manteia.
MGI - MGI:1919840
RefSeq - NM_028292
RefSeq Peptide - NP_082568
swissprot - A0A140LI84
swissprot - Q8BVQ5
Ensembl - ENSMUSG00000030718
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppme1ENSDARG00000009771Danio rerio
 PPME1ENSGALG00000017312Gallus gallus
 PPME1ENSG00000214517Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000073  Alpha/beta hydrolase fold-1
 IPR000639  Epoxide hydrolase-like
 IPR016812  Protein phosphatase methylesterase, eukaryotic
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006482 protein demethylation IBA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity IBA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0019903 protein phosphatase binding IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0051721 protein phosphatase 2A binding IEA
 molecular_functionGO:0051722 protein C-terminal methylesterase activity IEA
 molecular_functionGO:0051723 protein methylesterase activity IBA
 molecular_functionGO:0052689 carboxylic ester hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Cyclin A/B1/B2 associated events during G2/M transition


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001436 abnormal suckling behavior "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461]
Show

Allelic Composition: Mib1tm1Kong/Mib1tm1Kong
Genetic Background: involves: 129P2/OlaHsd

 MP:0001951 abnormal breathing "irregular or atypical breathing pattern " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:17489]
Show

Allelic Composition: Mib1tm1Kong/Mib1tm1Kong
Genetic Background: involves: 129P2/OlaHsd

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Mib1tm1Kong/Mib1tm1Kong
Genetic Background: involves: 129P2/OlaHsd

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Mib1tm1Kong/Mib1tm1Kong
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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