ENSG00000215788


Homo sapiens

Features
Gene ID: ENSG00000215788
  
Biological name :TNFRSF25
  
Synonyms : Q93038 / TNF receptor superfamily member 25 / TNFRSF25
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.31
Gene start: 6461151
Gene end: 6466195
  
Corresponding Affymetrix probe sets: 210847_x_at (Human Genome U133 Plus 2.0 Array)   211282_x_at (Human Genome U133 Plus 2.0 Array)   211841_s_at (Human Genome U133 Plus 2.0 Array)   216042_at (Human Genome U133 Plus 2.0 Array)   219423_x_at (Human Genome U133 Plus 2.0 Array)   237646_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431554
Ensembl peptide - ENSP00000434129
Ensembl peptide - ENSP00000465381
Ensembl peptide - ENSP00000314451
Ensembl peptide - ENSP00000326762
Ensembl peptide - ENSP00000337713
Ensembl peptide - ENSP00000349341
Ensembl peptide - ENSP00000367013
Ensembl peptide - ENSP00000404274
Ensembl peptide - ENSP00000421976
Ensembl peptide - ENSP00000423121
Ensembl peptide - ENSP00000424071
NCBI entrez gene - 8718     See in Manteia.
OMIM - 603366
RefSeq - NM_148967
RefSeq - NM_148970
RefSeq - NM_001039664
RefSeq - NM_003790
RefSeq - NM_148965
RefSeq - NM_148966
RefSeq Peptide - NP_683867
RefSeq Peptide - NP_683871
RefSeq Peptide - NP_001034753
RefSeq Peptide - NP_003781
RefSeq Peptide - NP_683866
RefSeq Peptide - NP_683868
swissprot - Q93038
swissprot - K7EJY9
swissprot - A0A0C4DGF3
Ensembl - ENSG00000215788
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-112c15.8ENSDARG00000089868Danio rerio
 ENSGALG00000026499Gallus gallus
 Tnfrsf25ENSMUSG00000024793Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P19438 / TNFRSF1A / TNF receptor superfamily member 1AENSG0000006718226


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR001368  TNFR/NGFR cysteine-rich region
 IPR011029  Death-like domain superfamily
 IPR022329  Tumour necrosis factor receptor 25
 IPR034050  Tumor necrosis factor receptor 25, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway TAS
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0097190 apoptotic signaling pathway TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005829 cytosol NAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005031 tumor necrosis factor-activated receptor activity TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
TNFs bind their physiological receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000181634 O95150 / TNFSF15 / TNF superfamily member 15  / reaction / complex






 

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