ENSG00000226784


Homo sapiens

Features
Gene ID: ENSG00000226784
  
Biological name :PGAM4
  
Synonyms : PGAM4 / phosphoglycerate mutase family member 4 / Q8N0Y7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: -1
Band: q21.1
Gene start: 77968874
Gene end: 77969638
  
Corresponding Affymetrix probe sets: 200886_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000412189
NCBI entrez gene - 441531     See in Manteia.
OMIM - 300567
RefSeq - NM_001029891
RefSeq Peptide - NP_001025062
swissprot - Q8N0Y7
Ensembl - ENSG00000226784
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pgam1aENSDARG00000005423Danio rerio
 pgam1bENSDARG00000014068Danio rerio
 PGAM1ENSGALG00000007606Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PGAM1 / P18669 / phosphoglycerate mutase 1ENSG0000017131496
PGAM2 / P15259 / phosphoglycerate mutase 2ENSG0000016470878
BPGM / P07738 / bisphosphoglycerate mutaseENSG0000017233152


Protein motifs (from Interpro)
Interpro ID Name
 IPR001345  Phosphoglycerate/bisphosphoglycerate mutase, active site
 IPR005952  Phosphoglycerate mutase 1
 IPR013078  Histidine phosphatase superfamily, clade-1
 IPR029033  Histidine phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006094 gluconeogenesis IBA
 biological_processGO:0006096 glycolytic process NAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0043456 regulation of pentose-phosphate shunt IBA
 biological_processGO:1902093 positive regulation of flagellated sperm motility NAS
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0097228 sperm principal piece IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004082 bisphosphoglycerate mutase activity IEA
 molecular_functionGO:0004619 phosphoglycerate mutase activity NAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0016868 intramolecular transferase activity, phosphotransferases IEA
 molecular_functionGO:0046538 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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