ENSG00000171314


Homo sapiens

Features
Gene ID: ENSG00000171314
  
Biological name :PGAM1
  
Synonyms : P18669 / PGAM1 / phosphoglycerate mutase 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q24.1
Gene start: 97426160
Gene end: 97433441
  
Corresponding Affymetrix probe sets: 200886_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359991
NCBI entrez gene - 5223     See in Manteia.
OMIM - 172250
RefSeq - NM_002629
RefSeq Peptide - NP_002620
swissprot - P18669
swissprot - Q6FHU2
Ensembl - ENSG00000171314
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pgam1aENSDARG00000005423Danio rerio
 pgam1bENSDARG00000014068Danio rerio
 PGAM1ENSGALG00000007606Gallus gallus
 Pgam1ENSMUSG00000011752Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PGAM4 / Q8N0Y7 / phosphoglycerate mutase family member 4ENSG0000022678496
PGAM2 / P15259 / phosphoglycerate mutase 2ENSG0000016470881
BPGM / P07738 / bisphosphoglycerate mutaseENSG0000017233154


Protein motifs (from Interpro)
Interpro ID Name
 IPR001345  Phosphoglycerate/bisphosphoglycerate mutase, active site
 IPR005952  Phosphoglycerate mutase 1
 IPR013078  Histidine phosphatase superfamily, clade-1
 IPR029033  Histidine phosphatase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006094 gluconeogenesis TAS
 biological_processGO:0006096 glycolytic process IDA
 biological_processGO:0006110 regulation of glycolytic process IDA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0043456 regulation of pentose-phosphate shunt IDA
 biological_processGO:0045730 respiratory burst IDA
 biological_processGO:0061621 canonical glycolysis TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0034774 secretory granule lumen TAS
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004082 bisphosphoglycerate mutase activity IEA
 molecular_functionGO:0004619 phosphoglycerate mutase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0016868 intramolecular transferase activity, phosphotransferases IEA
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0046538 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity IBA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Glycolysis
Gluconeogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000171314 PGAM1 / P18669 / phosphoglycerate mutase 1  / complex






 

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