ENSG00000239282


Homo sapiens

Features
Gene ID: ENSG00000239282
  
Biological name :CASTOR1
  
Synonyms : CASTOR1 / cytosolic arginine sensor for mTORC1 subunit 1 / Q8WTX7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q12.2
Gene start: 30285117
Gene end: 30289627
  
Corresponding Affymetrix probe sets: 226613_at (Human Genome U133 Plus 2.0 Array)   233528_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000408419
Ensembl peptide - ENSP00000411842
Ensembl peptide - ENSP00000416041
Ensembl peptide - ENSP00000384183
Ensembl peptide - ENSP00000385868
Ensembl peptide - ENSP00000390869
Ensembl peptide - ENSP00000407871
NCBI entrez gene - 652968     See in Manteia.
OMIM - 617034
RefSeq - NM_001037666
RefSeq Peptide - NP_001032755
swissprot - F2Z3I9
swissprot - F8WD52
swissprot - H7C2U7
swissprot - B7WPJ3
swissprot - Q8WTX7
swissprot - F2Z2C1
Ensembl - ENSG00000239282
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 castor1ENSDARG00000107096Danio rerio
 CASTOR1ENSGALG00000007964Gallus gallus
 Gatsl3ENSMUSG00000020424Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
A6NHX0 / CASTOR2 / cytosolic arginine sensor for mTORC1 subunit 2ENSG0000027407063
Q8NAP1 / CASTOR3 / CASTOR family member 3ENSG0000023952124


Protein motifs (from Interpro)
Interpro ID Name
 IPR026249  CASTOR family
 IPR027795  CASTOR, ACT domain
 IPR030415  Cytosolic arginine sensor for mTORC1 subunit 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:1903432 regulation of TORC1 signaling IEA
 biological_processGO:1903577 cellular response to L-arginine IMP
 biological_processGO:1904262 negative regulation of TORC1 signaling IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0061700 GATOR2 complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0034618 arginine binding IDA
 molecular_functionGO:0042802 identical protein binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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