ENSG00000248329


Homo sapiens

Features
Gene ID: ENSG00000248329
  
Biological name :APELA
  
Synonyms : APELA / apelin receptor early endogenous ligand / P0DMC3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q32.3
Gene start: 164877004
Gene end: 164898965
  
Corresponding Affymetrix probe sets: 1559280_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478306
Ensembl peptide - ENSP00000480045
Ensembl peptide - ENSP00000484618
NCBI entrez gene - 100506013     See in Manteia.
OMIM - 615594
RefSeq - XM_017007623
RefSeq - NM_001297550
RefSeq Peptide - NP_001284479
swissprot - P0DMC3
swissprot - X5D2P3
Ensembl - ENSG00000248329
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 APELAENSGALG00000023444Gallus gallus
 ApelaENSMUSG00000079042Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0001570 vasculogenesis ISS
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007369 gastrulation IEA
 biological_processGO:0007492 endoderm development ISS
 biological_processGO:0007507 heart development ISS
 biological_processGO:0007509 mesoderm migration involved in gastrulation ISS
 biological_processGO:0007512 adult heart development ISS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0035050 embryonic heart tube development ISS
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0045823 positive regulation of heart contraction ISS
 biological_processGO:0060183 apelin receptor signaling pathway ISS
 biological_processGO:0060395 SMAD protein signal transduction IEA
 biological_processGO:0060674 placenta blood vessel development ISS
 biological_processGO:0060976 coronary vasculature development ISS
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISS
 biological_processGO:0090133 mesendoderm migration ISS
 biological_processGO:0090134 cell migration involved in mesendoderm migration ISS
 biological_processGO:1901165 positive regulation of trophoblast cell migration IMP
 biological_processGO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis ISS
 biological_processGO:1904022 positive regulation of G-protein coupled receptor internalization IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005179 hormone activity ISS
 molecular_functionGO:0031704 apelin receptor binding ISS


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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