ENSG00000250799


Homo sapiens

Features
Gene ID: ENSG00000250799
  
Biological name :PRODH2
  
Synonyms : PRODH2 / proline dehydrogenase 2 / Q9UF12
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.12
Gene start: 35799988
Gene end: 35813299
  
Corresponding Affymetrix probe sets: 216696_s_at (Human Genome U133 Plus 2.0 Array)   243614_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000301175
Ensembl peptide - ENSP00000465214
Ensembl peptide - ENSP00000474199
NCBI entrez gene - 58510     See in Manteia.
OMIM - 616377
RefSeq - XM_017027085
RefSeq - NM_021232
RefSeq - XM_017027084
RefSeq Peptide - NP_067055
swissprot - Q9UF12
swissprot - S4R3D8
swissprot - K7EJK5
Ensembl - ENSG00000250799
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:92040ENSDARG00000021154Danio rerio
 Prodh2ENSMUSG00000036892Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRODH / O43272 / proline dehydrogenase 1ENSG0000010003334


Protein motifs (from Interpro)
Interpro ID Name
 IPR002872  Proline dehydrogenase domain
 IPR015659  Proline oxidase family
 IPR029041  FAD-linked oxidoreductase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006560 proline metabolic process IEA
 biological_processGO:0006562 proline catabolic process IEA
 biological_processGO:0010133 proline catabolic process to glutamate IBA
 biological_processGO:0046487 glyoxylate metabolic process TAS
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane IEA
 molecular_functionGO:0004657 proline dehydrogenase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016645 oxidoreductase activity, acting on the CH-NH group of donors IDA
 molecular_functionGO:0071949 FAD binding IBA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Proline catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000250799 PRODH2 / Q9UF12 / proline dehydrogenase 2  / complex






 

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