ENSG00000256683


Homo sapiens

Features
Gene ID: ENSG00000256683
  
Biological name :ZNF350
  
Synonyms : Q9GZX5 / zinc finger protein 350 / ZNF350
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.41
Gene start: 51964343
Gene end: 51986856
  
Corresponding Affymetrix probe sets: 219266_at (Human Genome U133 Plus 2.0 Array)   233169_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000469594
Ensembl peptide - ENSP00000470930
Ensembl peptide - ENSP00000472104
Ensembl peptide - ENSP00000243644
Ensembl peptide - ENSP00000470066
NCBI entrez gene - 59348     See in Manteia.
OMIM - 605422
RefSeq - XM_017027104
RefSeq - XM_017027098
RefSeq - XM_017027099
RefSeq - XM_017027100
RefSeq - XM_017027101
RefSeq - XM_017027102
RefSeq - XM_017027103
RefSeq - NM_021632
RefSeq - XM_011527196
RefSeq - XM_017027094
RefSeq - XM_017027095
RefSeq - XM_017027096
RefSeq - XM_017027097
RefSeq Peptide - NP_067645
swissprot - M0QYT6
swissprot - M0R017
swissprot - M0R1T8
swissprot - M0QY52
swissprot - Q9GZX5
Ensembl - ENSG00000256683
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6PF04 / ZNF613 / zinc finger protein 613ENSG0000017602463
Q9BS31 / ZNF649 / zinc finger protein 649ENSG0000019809354
Q9BSK1 / ZNF577 / zinc finger protein 577ENSG0000016155146
Q8N883 / ZNF614 / zinc finger protein 614ENSG0000014255644
AC026786.1ENSG0000025682513


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0016363 nuclear matrix IEA
 cellular_componentGO:0016604 nuclear body IDA
 cellular_componentGO:0017053 transcriptional repressor complex IDA
 molecular_functionGO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway
SUMOylation of transcription cofactors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000130726 Q13263 / TRIM28 / tripartite motif containing 28  / complex
 ENSG00000103275 UBE2I / P63279 / ubiquitin conjugating enzyme E2 I  / reaction
 ENSG00000116030 SUMO1 / P63165 / small ubiquitin-like modifier 1  / reaction






 

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