ENSG00000256771


Homo sapiens

Features
Gene ID: ENSG00000256771
  
Biological name :ZNF253
  
Synonyms : O75346 / zinc finger protein 253 / ZNF253
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.11
Gene start: 19865886
Gene end: 19894674
  
Corresponding Affymetrix probe sets: 206900_x_at (Human Genome U133 Plus 2.0 Array)   242919_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000467235
Ensembl peptide - ENSP00000492582
Ensembl peptide - ENSP00000468720
Ensembl peptide - ENSP00000347868
NCBI entrez gene - 56242     See in Manteia.
OMIM - 606954
RefSeq - NM_001331134
RefSeq - NM_021047
RefSeq Peptide - NP_001318063
RefSeq Peptide - NP_066385
swissprot - O75346
swissprot - K7EP55
swissprot - A0A1W2PRC0
Ensembl - ENSG00000256771
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CT573016.1ENSMUSG00000114923Mus musculus
 Zfp457ENSMUSG00000055341Mus musculus
 Zfp595ENSMUSG00000057842Mus musculus
 Zfp65ENSMUSG00000071281Mus musculus
 Zfp759ENSMUSG00000057396Mus musculus
 Zfp953ENSMUSG00000098905Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5JVG8 / ZNF506 / zinc finger protein 506ENSG0000008166569
O75373 / ZNF737 / zinc finger protein 737ENSG0000023744069
ZNF43 / P17038 / zinc finger protein 43ENSG0000019852169
ZNF66 / Q6ZN08 / zinc finger protein 66ENSG0000016022968
ZNF90 / Q03938 / zinc finger protein 90ENSG0000021398868
ZNF98 / A6NK75 / zinc finger protein 98ENSG0000019736067
Q96H40 / ZNF486 / zinc finger protein 486ENSG0000025622967
Q96N22 / ZNF681 / zinc finger protein 681ENSG0000019617267
ZNF92 / Q03936 / zinc finger protein 92ENSG0000014675767
Q9UII5 / ZNF107 / zinc finger protein 107ENSG0000019624767
O75437 / ZNF254 / zinc finger protein 254ENSG0000021309666
ZNF85 / Q03923 / zinc finger protein 85ENSG0000010575066
A6NNF4 / ZNF726 / zinc finger protein 726ENSG0000021396766
Q86V71 / ZNF429 / zinc finger protein 429ENSG0000019701366
Q9H8G1 / ZNF430 / zinc finger protein 430ENSG0000011862065
Q68DY1 / ZNF626 / zinc finger protein 626ENSG0000018817165
Q6ZR52 / ZNF493 / zinc finger protein 493ENSG0000019626865
Q8TF32 / ZNF431 / zinc finger protein 431ENSG0000019670564
P0DKX0 / ZNF728 / zinc finger protein 728ENSG0000026906764
Q9Y2Q1 / ZNF257 / zinc finger protein 257ENSG0000019713463


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated NAS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding NAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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