ENSG00000266964


Homo sapiens

Features
Gene ID: ENSG00000266964
  
Biological name :FXYD1
  
Synonyms : FXYD1 / FXYD domain containing ion transport regulator 1 / O00168
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.12
Gene start: 35138808
Gene end: 35143109
  
Corresponding Affymetrix probe sets: 205384_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481244
Ensembl peptide - ENSP00000467818
Ensembl peptide - ENSP00000468535
Ensembl peptide - ENSP00000343314
Ensembl peptide - ENSP00000393611
Ensembl peptide - ENSP00000465289
Ensembl peptide - ENSP00000466398
Ensembl peptide - ENSP00000467727
NCBI entrez gene - 5348     See in Manteia.
OMIM - 602359
RefSeq - XM_017026876
RefSeq - NM_001278717
RefSeq - NM_001278718
RefSeq - NM_005031
RefSeq - NM_021902
RefSeq - XM_017026874
RefSeq - XM_017026875
RefSeq Peptide - NP_005022
RefSeq Peptide - NP_068702
RefSeq Peptide - NP_001265646
RefSeq Peptide - NP_001265647
swissprot - O00168
swissprot - K7EQG4
Ensembl - ENSG00000266964
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fxyd6lENSDARG00000097057Danio rerio
 Fxyd1ENSMUSG00000036570Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FXYD6 / Q9H0Q3 / FXYD domain containing ion transport regulator 6ENSG0000013772642
FXYD6-FXYD2 / FXYD6-FXYD2 readthroughENSG0000025524540
FXYD2 / P54710 / FXYD domain containing ion transport regulator 2ENSG0000013773128


Protein motifs (from Interpro)
Interpro ID Name
 IPR000272  Ion-transport regulator, FXYD motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006821 chloride transport TAS
 biological_processGO:0006936 muscle contraction TAS
 biological_processGO:0008016 regulation of heart contraction TAS
 biological_processGO:0010734 negative regulation of protein glutathionylation ISS
 biological_processGO:0034220 ion transmembrane transport TAS
 biological_processGO:0086036 regulation of cardiac muscle cell membrane potential IEA
 biological_processGO:1902476 chloride transmembrane transport IEA
 biological_processGO:1903278 positive regulation of sodium ion export across plasma membrane IEA
 biological_processGO:1903779 regulation of cardiac conduction TAS
 biological_processGO:2000649 regulation of sodium ion transmembrane transporter activity IEA
 cellular_componentGO:0005886 plasma membrane NAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005890 sodium:potassium-exchanging ATPase complex ISS
 cellular_componentGO:0005901 caveola ISS
 cellular_componentGO:0014704 intercalated disc ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISS
 cellular_componentGO:0030315 T-tubule ISS
 cellular_componentGO:0042383 sarcolemma ISS
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005254 chloride channel activity TAS
 molecular_functionGO:0017080 sodium channel regulator activity IEA
 molecular_functionGO:0044325 ion channel binding ISS


Pathways (from Reactome)
Pathway description
Ion homeostasis
Ion transport by P-type ATPases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr