ENSG00000267680


Homo sapiens

Features
Gene ID: ENSG00000267680
  
Biological name :ZNF224
  
Synonyms : Q9NZL3 / zinc finger protein 224 / ZNF224
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.31
Gene start: 44094339
Gene end: 44109886
  
Corresponding Affymetrix probe sets: 216983_s_at (Human Genome U133 Plus 2.0 Array)   220019_s_at (Human Genome U133 Plus 2.0 Array)   229123_at (Human Genome U133 Plus 2.0 Array)   232427_at (Human Genome U133 Plus 2.0 Array)   244462_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000337368
Ensembl peptide - ENSP00000465000
Ensembl peptide - ENSP00000465886
Ensembl peptide - ENSP00000466961
NCBI entrez gene - 7767     See in Manteia.
OMIM - 194555
RefSeq - XM_017027261
RefSeq - NM_001321645
RefSeq - NM_013398
RefSeq Peptide - NP_001308574
RefSeq Peptide - NP_037530
swissprot - Q9NZL3
swissprot - K7EJ30
swissprot - K7EL24
swissprot - K7ENI7
Ensembl - ENSG00000267680
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 znf993ENSDARG00000110787Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UK10 / ZNF225 / zinc finger protein 225ENSG0000025629474
ZNF221 / zinc finger protein 221ENSG0000015990564
Q2VY69 / ZNF284 / zinc finger protein 284ENSG0000018602660
Q14588 / ZNF234 / zinc finger protein 234ENSG0000026300259
Q12901 / ZNF155 / zinc finger protein 155ENSG0000020492057
Q9NYT6 / ZNF226 / zinc finger protein 226ENSG0000016738056
Q14590 / ZNF235 / zinc finger protein 235ENSG0000015991749
Q9UK12 / ZNF222 / zinc finger protein 222ENSG0000015988548
AC067968.1ENSG0000026702248
ZNF45 / Q02386 / zinc finger protein 45ENSG0000012445948
Q9UK11 / ZNF223 / zinc finger protein 223ENSG0000017838648
Q86WZ6 / ZNF227 / zinc finger protein 227ENSG0000013111547
Q9UIE0 / ZNF230 / zinc finger protein 230ENSG0000015988247
Q9UJU3 / ZNF112 / zinc finger protein 112ENSG0000006237046
Q9UJW7 / ZNF229 / zinc finger protein 229ENSG0000027831846
A6NK53 / ZNF233 / zinc finger protein 233ENSG0000015991536
Q96NJ3 / ZNF285 / zinc finger protein 285ENSG0000026750834
Q9UL59 / ZNF214 / zinc finger protein 214ENSG0000014905033
Q16600 / ZNF239 / zinc finger protein 239ENSG0000019679323
Q8N3J9 / ZNF664 / zinc finger protein 664ENSG0000017919519


Protein motifs (from Interpro)
Interpro ID Name
 IPR001909  Krueppel-associated box
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0017053 transcriptional repressor complex IDA
 cellular_componentGO:0031965 nuclear membrane IDA
 molecular_functionGO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Generic Transcription Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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