ENSG00000276644


Homo sapiens

Features
Gene ID: ENSG00000276644
  
Biological name :DACH1
  
Synonyms : DACH1 / dachshund family transcription factor 1 / Q9UI36
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q21.33
Gene start: 71437966
Gene end: 71867192
  
Corresponding Affymetrix probe sets: 205471_s_at (Human Genome U133 Plus 2.0 Array)   205472_s_at (Human Genome U133 Plus 2.0 Array)   228915_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000482245
Ensembl peptide - ENSP00000482797
Ensembl peptide - ENSP00000482493
Ensembl peptide - ENSP00000481551
NCBI entrez gene - 1602     See in Manteia.
OMIM - 603803
RefSeq - XM_017020396
RefSeq - NM_004392
RefSeq - NM_080759
RefSeq - NM_080760
RefSeq - XM_011534939
RefSeq - XM_011534942
RefSeq Peptide - NP_542938
RefSeq Peptide - NP_542937
RefSeq Peptide - NP_004383
swissprot - A0A087WY66
swissprot - A0A087WZA7
swissprot - A0A087WZP2
swissprot - Q9UI36
Ensembl - ENSG00000276644
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dachcENSDARG00000003142Danio rerio
 dachdENSDARG00000069440Danio rerio
 DACH1ENSGALG00000037015Gallus gallus
 Dach1ENSMUSG00000055639Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DACH2 / Q96NX9 / dachshund family transcription factor 2ENSG0000012673344


Protein motifs (from Interpro)
Interpro ID Name
 IPR003380  SKI/SNO/DAC domain
 IPR009061  Putative DNA-binding domain superfamily
 IPR037000  Ski-like, DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001967 suckling behavior IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007585 respiratory gaseous exchange IEA
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0010944 negative regulation of transcription by competitive promoter binding IMP
 biological_processGO:0030336 negative regulation of cell migration IDA
 biological_processGO:0033262 regulation of nuclear cell cycle DNA replication IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IMP
 biological_processGO:0046545 development of primary female sexual characteristics IEA
 biological_processGO:0048147 negative regulation of fibroblast proliferation IEA
 biological_processGO:0051123 RNA polymerase II transcriptional preinitiation complex assembly IEA
 biological_processGO:0060244 negative regulation of cell proliferation involved in contact inhibition IEA
 biological_processGO:2000279 negative regulation of DNA biosynthetic process IDA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005667 transcription factor complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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