ENSG00000277363


Homo sapiens

Features
Gene ID: ENSG00000277363
  
Biological name :SRCIN1
  
Synonyms : Q9C0H9 / SRCIN1 / SRC kinase signaling inhibitor 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q12
Gene start: 38530016
Gene end: 38605930
  
Corresponding Affymetrix probe sets: 1554759_at (Human Genome U133 Plus 2.0 Array)   232547_at (Human Genome U133 Plus 2.0 Array)   236838_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000477811
Ensembl peptide - ENSP00000484715
Ensembl peptide - ENSP00000483931
Ensembl peptide - ENSP00000479718
Ensembl peptide - ENSP00000478342
NCBI entrez gene - 80725     See in Manteia.
OMIM - 610786
RefSeq - XM_017025169
RefSeq - XM_017025171
RefSeq - XM_017025172
RefSeq - XM_017025173
RefSeq - XM_017025174
RefSeq - XM_017025170
RefSeq - NM_025248
RefSeq Peptide - NP_079524
swissprot - Q9C0H9
swissprot - A0A087WVV7
swissprot - A0A087WU33
swissprot - A0A087WTE6
swissprot - A0A087X165
Ensembl - ENSG00000277363
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-278a6.1ENSDARG00000059773Danio rerio
 zgc:114120ENSDARG00000101812Danio rerio
 SRCIN1ENSGALG00000032628Gallus gallus
 Srcin1ENSMUSG00000038453Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5T5P2 / KIAA1217ENSG0000012054936


Protein motifs (from Interpro)
Interpro ID Name
 IPR022782  Actin interacting protein 3-like, C-terminal
 IPR026727  SRC kinase signalling inhibitor 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0030334 regulation of cell migration IEA
 biological_processGO:0034446 substrate adhesion-dependent cell spreading IEA
 biological_processGO:0050709 negative regulation of protein secretion IEA
 biological_processGO:0061001 regulation of dendritic spine morphogenesis IEA
 biological_processGO:0061098 positive regulation of protein tyrosine kinase activity IDA
 biological_processGO:0061099 negative regulation of protein tyrosine kinase activity IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0014069 postsynaptic density ISS
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0045202 synapse ISS
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IDA
 molecular_functionGO:0019904 protein domain specific binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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