ENSGALG00000000255


Gallus gallus

Features
Gene ID: ENSGALG00000000255
  
Biological name :MAN2A1
  
Synonyms : MAN2A1 / mannosidase alpha class 2A member 1
  
Possible biological names infered from orthology : Alpha-mannosidase 2 / P27046 / Q16706
  
Species: Gallus gallus
  
Chr. number: Z
Strand: -1
Band:
Gene start: 47154837
Gene end: 47271874
  
Corresponding Affymetrix probe sets: Gga.17644.1.S1_at (Chicken Array)   Gga.17667.1.S1_at (Chicken Array)   GgaAffx.155.1.S1_at (Chicken Array)   GgaAffx.156.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000000333
NCBI entrez gene - 415611     See in Manteia.
RefSeq - XM_003643046
swissprot - F1NKR1
Ensembl - ENSGALG00000000255
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 man2a1ENSDARG00000102200Danio rerio
 MAN2A1ENSG00000112893Homo sapiens
 Man2a1ENSMUSG00000024085Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MAN2A2 / mannosidase alpha class 2A member 2 / P49641* / Q8BRK9* / Alpha-mannosidase 2x *ENSGALG0000003379058
MAN2B2 / mannosidase alpha class 2B member 2 / Q9Y2E5* / Mrfap1* / Q9CQL7* / MORF4 family-associated protein 1 *ENSGALG0000001553721


Protein motifs (from Interpro)
Interpro ID Name
 IPR000602  Glycoside hydrolase family 38, N-terminal domain
 IPR011013  Galactose mutarotase-like domain superfamily
 IPR011330  Glycoside hydrolase/deacetylase, beta/alpha-barrel
 IPR011682  Glycosyl hydrolase family 38, C-terminal
 IPR013780  Glycosyl hydrolase, all-beta
 IPR015341  Glycoside hydrolase family 38, central domain
 IPR027291  Glycoside hydrolase 38, N-terminal domain superfamily
 IPR028995  Glycoside hydrolase families 57/38, central domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0006013 mannose metabolic process IBA
 biological_processGO:0006491 N-glycan processing IEA
 biological_processGO:0006517 protein deglycosylation IBA
 biological_processGO:0007005 mitochondrion organization IEA
 biological_processGO:0007033 vacuole organization IEA
 biological_processGO:0007585 respiratory gaseous exchange IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0048286 lung alveolus development IEA
 biological_processGO:0050769 positive regulation of neurogenesis IEA
 biological_processGO:0060042 retina morphogenesis in camera-type eye IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005797 Golgi medial cisterna IEA
 cellular_componentGO:0005801 cis-Golgi network IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004559 alpha-mannosidase activity IBA
 molecular_functionGO:0015923 mannosidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Reactions specific to the complex N-glycan synthesis pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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