ENSGALG00000001506


Gallus gallus

Features
Gene ID: ENSGALG00000001506
  
Biological name :PTTG1
  
Synonyms : PTTG1 / securin isoform 1
  
Possible biological names infered from orthology : O95997 / pituitary tumor-transforming 1 / pituitary tumor-transforming 2 / PTTG2 / Q9CQJ7 / Q9NZH5 / Securin
  
Species: Gallus gallus
  
Chr. number: 13
Strand: -1
Band:
Gene start: 7818158
Gene end: 7821302
  
Corresponding Affymetrix probe sets: Gga.1281.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000056129
Ensembl peptide - ENSGALP00000063102
Ensembl peptide - ENSGALP00000062623
Ensembl peptide - ENSGALP00000061518
Ensembl peptide - ENSGALP00000002289
NCBI entrez gene - 416158     See in Manteia.
RefSeq - NM_001277740
RefSeq - NM_001277741
RefSeq Peptide - NP_001264670
RefSeq Peptide - NP_001264669
swissprot - A0A1D5PT86
swissprot - E1BU16
swissprot - A0A1L1RRU0
Ensembl - ENSGALG00000001506
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PTTG1ENSG00000164611Homo sapiens
 PTTG2ENSG00000250254Homo sapiens
 Pttg1ENSMUSG00000020415Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006940  Securin sister-chromatid separation inhibitor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IBA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0007064 mitotic sister chromatid cohesion IEA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0045143 homologous chromosome segregation IBA
 biological_processGO:0051276 chromosome organization IEA
 biological_processGO:2000816 negative regulation of mitotic sister chromatid separation IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004869 cysteine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0030414 peptidase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Separation of Sister Chromatids


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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