ENSGALG00000002165


Gallus gallus

Features
Gene ID: ENSGALG00000002165
  
Biological name :UNC13B
  
Synonyms : UNC13B / unc-13 homolog B
  
Possible biological names infered from orthology : O14795 / Q9Z1N9 / unc-13 homolog B (C. elegans)
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 8647604
Gene end: 8854766
  
Corresponding Affymetrix probe sets: GgaAffx.1407.1.S1_at (Chicken Array)   GgaAffx.1440.2.S1_s_at (Chicken Array)   GgaAffx.1440.5.S1_at (Chicken Array)   GgaAffx.1440.5.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000003389
NCBI entrez gene - 100858799     See in Manteia.
RefSeq - XM_004937124
RefSeq - XM_004937125
RefSeq - XM_004937126
RefSeq - XM_004937127
RefSeq - XM_015277471
RefSeq - XM_015277472
RefSeq - XM_015277473
RefSeq - XM_015277475
RefSeq - XM_004937123
swissprot - F1NY18
Ensembl - ENSGALG00000002165
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 unc13baENSDARG00000017391Danio rerio
 unc-13 homolog BENSDARG00000099113Danio rerio
 O14795ENSG00000198722Homo sapiens
 Q9Z1N9ENSMUSG00000028456Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000004137180
UNC13C / unc-13 homolog C / Q8K0T7* / Q8NB66* / unc-13 homolog C (C. elegans)*ENSGALG0000003593558


Protein motifs (from Interpro)
Interpro ID Name
 IPR000008  C2 domain
 IPR002219  Protein kinase C-like, phorbol ester/diacylglycerol-binding domain
 IPR010439  Calcium-dependent secretion activator domain
 IPR014770  Munc13 homology 1
 IPR014772  Mammalian uncoordinated homology 13, domain 2
 IPR019558  Mammalian uncoordinated homology 13, subgroup, domain 2
 IPR027080  Protein Unc-13


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007268 chemical synaptic transmission IEA
 biological_processGO:0007528 neuromuscular junction development IEA
 biological_processGO:0016079 synaptic vesicle exocytosis IBA
 biological_processGO:0016081 synaptic vesicle docking IEA
 biological_processGO:0016082 synaptic vesicle priming IEA
 biological_processGO:0031914 negative regulation of synaptic plasticity IEA
 biological_processGO:0035249 synaptic transmission, glutamatergic IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0048172 regulation of short-term neuronal synaptic plasticity IEA
 biological_processGO:0050714 positive regulation of protein secretion IEA
 biological_processGO:0060384 innervation IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0090382 phagosome maturation IEA
 biological_processGO:0099525 presynaptic dense core vesicle exocytosis IEA
 biological_processGO:1900426 positive regulation of defense response to bacterium IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031594 neuromuscular junction IEA
 cellular_componentGO:0032009 early phagosome IEA
 cellular_componentGO:0043195 terminal bouton IBA
 cellular_componentGO:0044305 calyx of Held IEA
 cellular_componentGO:0048786 presynaptic active zone IEA
 cellular_componentGO:0097470 ribbon synapse IEA
 cellular_componentGO:0098793 presynapse IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0019992 diacylglycerol binding IEA
 molecular_functionGO:0030742 GTP-dependent protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Norepinephrine Neurotransmitter Release Cycle
Glutamate Neurotransmitter Release Cycle
Acetylcholine Neurotransmitter Release Cycle


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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