ENSGALG00000002632


Gallus gallus

Features
Gene ID: ENSGALG00000002632
  
Biological name :CALCRL
  
Synonyms : calcitonin receptor like receptor / CALCRL
  
Possible biological names infered from orthology : Calcitonin-related peptide type 1 receptor / Q16602 / Q9R1W5
  
Species: Gallus gallus
  
Chr. number: 7
Strand: 1
Band:
Gene start: 1088699
Gene end: 1148350
  
Corresponding Affymetrix probe sets: Gga.10326.1.S1_s_at (Chicken Array)   GgaAffx.25557.1.S1_at (Chicken Array)   GgaAffx.25557.2.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000004138
NCBI entrez gene - 423990     See in Manteia.
RefSeq - NM_001163650
RefSeq Peptide - NP_001157122
swissprot - C5HV42
Ensembl - ENSGALG00000002632
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 calcrlaENSDARG00000011473Danio rerio
 calcrlbENSDARG00000011571Danio rerio
 CALCRLENSG00000064989Homo sapiens
 CalcrlENSMUSG00000059588Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ENSGALG0000000950961
CRHR1 / corticotropin-releasing factor receptor 1 precursor / P35347* / P34998* / LINC02210-CRHR1* / LINC02210-CRHR1 readthrough* / Corticotropin-releasing factor receptor 1 * / corticotro...ENSGALG0000000037126
CRHR2 / corticotropin-releasing factor receptor 2 / Q13324* / Q60748* / corticotropin releasing hormone receptor 2*ENSGALG0000000565725


Protein motifs (from Interpro)
Interpro ID Name
 IPR000832  GPCR, family 2, secretin-like
 IPR001879  GPCR, family 2, extracellular hormone receptor domain
 IPR003287  GPCR, family 2, calcitonin receptor family
 IPR003289  GPCR, family 2, calcitonin gene-related peptide, type 1 receptor
 IPR017981  GPCR, family 2-like
 IPR017983  GPCR, family 2, secretin-like, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007507 heart development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0031623 receptor internalization IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0071329 cellular response to sucrose stimulus IEA
 biological_processGO:1990408 calcitonin gene-related peptide receptor signaling pathway IEA
 biological_processGO:1990410 adrenomedullin receptor signaling pathway IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:1903143 adrenomedullin receptor complex IEA
 cellular_componentGO:1990406 CGRP receptor complex IEA
 molecular_functionGO:0001605 adrenomedullin receptor activity IEA
 molecular_functionGO:0001635 calcitonin gene-related peptide receptor activity IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004948 calcitonin receptor activity IEA
 molecular_functionGO:0008565 protein transporter activity IEA
 molecular_functionGO:1990409 adrenomedullin binding IEA


Pathways (from Reactome)
Pathway description
G alpha (s) signalling events
Calcitonin-like ligand receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000024449 RAMP2 / receptor activity modifying protein 2 / O60895* / Q9WUP0*  / complex
 ENSGALG00000046593 ADM / adrenomedullin / P35318* / P97297* / ADM Adrenomedullin Proadrenomedullin N-20 terminal peptide*  / reaction / complex
 ENSGALG00000003821 RAMP1 / receptor activity modifying protein 1 / O60894* / Q9WTJ5* / receptor (calcitonin) activity modifying protein 1*  / complex
 ENSGALG00000006054 CALCB / calcitonin gene-related peptide isoform 3 preproprotein / CALCA* / P01258* / P06881* / P70160* / Q99JA0* / Calcitonin-related peptide 1 * / calcitonin related polypeptide alpha*  / reaction / complex
 ENSGALG00000037246 RAMP3 / receptor activity modifying protein 3 / O60896* / Q9WUP1*  / complex






 

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