ENSGALG00000003547


Gallus gallus

Features
Gene ID: ENSGALG00000003547
  
Biological name :SKP2
  
Synonyms : SKP2 / S-phase kinase-associated protein 2
  
Possible biological names infered from orthology : Q13309 / Q9Z0Z3 / S-phase kinase-associated protein 2 (p45)
  
Species: Gallus gallus
  
Chr. number: Z
Strand: 1
Band:
Gene start: 10979414
Gene end: 10990078
  
Corresponding Affymetrix probe sets: GgaAffx.11588.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000005599
NCBI entrez gene - 427437     See in Manteia.
RefSeq - NM_001007982
RefSeq - XM_015277331
RefSeq Peptide - NP_001007983
swissprot - F7BEK8
Ensembl - ENSGALG00000003547
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 skp2ENSDARG00000004937Danio rerio
 SKP2ENSG00000145604Homo sapiens
 Skp2ENSMUSG00000054115Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR006553  Leucine-rich repeat, cysteine-containing subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IEA
 biological_processGO:0000086 G2/M transition of mitotic cell cycle IEA
 biological_processGO:0000209 protein polyubiquitination IEA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0033148 positive regulation of intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:1902916 positive regulation of protein polyubiquitination IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
SCF(Skp2)-mediated degradation of p27/p21
Ub-specific processing proteases
Orc1 removal from chromatin
Cyclin D associated events in G1
Regulation of RUNX2 expression and activity
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr