ENSGALG00000004170


Gallus gallus

Features
Gene ID: ENSGALG00000004170
  
Biological name :ADA
  
Synonyms : ADA / adenosine deaminase
  
Possible biological names infered from orthology : P00813 / P03958
  
Species: Gallus gallus
  
Chr. number: 20
Strand: 1
Band:
Gene start: 5501132
Gene end: 5513764
  
Corresponding Affymetrix probe sets: Gga.9054.1.S1_s_at (Chicken Array)   Gga.9094.1.A1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000050849
Ensembl peptide - ENSGALP00000006620
NCBI entrez gene - 419194     See in Manteia.
RefSeq - NM_001006290
RefSeq Peptide - NP_001006290
swissprot - F1P2A6
swissprot - A0A1D5PDK4
Ensembl - ENSGALG00000004170
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 adaENSDARG00000003113Danio rerio
 ADAENSG00000196839Homo sapiens
 AdaENSMUSG00000017697Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001365  Adenosine/AMP deaminase domain
 IPR006330  Adenosine/adenine deaminase
 IPR006650  Adenosine/AMP deaminase active site
 IPR028893  Adenosine deaminase
 IPR032466  Metal-dependent hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0001829 trophectodermal cell differentiation IEA
 biological_processGO:0001889 liver development IEA
 biological_processGO:0001890 placenta development IEA
 biological_processGO:0002314 germinal center B cell differentiation IEA
 biological_processGO:0002636 positive regulation of germinal center formation IEA
 biological_processGO:0002686 negative regulation of leukocyte migration IEA
 biological_processGO:0002906 negative regulation of mature B cell apoptotic process IEA
 biological_processGO:0006154 adenosine catabolic process IEA
 biological_processGO:0006157 deoxyadenosine catabolic process IEA
 biological_processGO:0009168 purine ribonucleoside monophosphate biosynthetic process IEA
 biological_processGO:0010460 positive regulation of heart rate IEA
 biological_processGO:0030324 lung development IEA
 biological_processGO:0030890 positive regulation of B cell proliferation IEA
 biological_processGO:0032261 purine nucleotide salvage IEA
 biological_processGO:0033089 positive regulation of T cell differentiation in thymus IEA
 biological_processGO:0033632 regulation of cell-cell adhesion mediated by integrin IEA
 biological_processGO:0042110 T cell activation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0045580 regulation of T cell differentiation IEA
 biological_processGO:0045582 positive regulation of T cell differentiation IEA
 biological_processGO:0045987 positive regulation of smooth muscle contraction IEA
 biological_processGO:0046061 dATP catabolic process IEA
 biological_processGO:0046101 hypoxanthine biosynthetic process IEA
 biological_processGO:0046103 inosine biosynthetic process IEA
 biological_processGO:0046111 xanthine biosynthetic process IEA
 biological_processGO:0046638 positive regulation of alpha-beta T cell differentiation IEA
 biological_processGO:0048286 lung alveolus development IEA
 biological_processGO:0048541 Peyer"s patch development IEA
 biological_processGO:0048566 embryonic digestive tract development IEA
 biological_processGO:0050728 negative regulation of inflammatory response IEA
 biological_processGO:0050850 positive regulation of calcium-mediated signaling IEA
 biological_processGO:0050862 positive regulation of T cell receptor signaling pathway IEA
 biological_processGO:0050870 positive regulation of T cell activation IEA
 biological_processGO:0060169 negative regulation of adenosine receptor signaling pathway IEA
 biological_processGO:0060407 negative regulation of penile erection IEA
 biological_processGO:0070244 negative regulation of thymocyte apoptotic process IEA
 biological_processGO:0070256 negative regulation of mucus secretion IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0004000 adenosine deaminase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019239 deaminase activity IEA


Pathways (from Reactome)
Pathway description
Purine salvage


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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