ENSGALG00000004758


Gallus gallus

Features
Gene ID: ENSGALG00000004758
  
Biological name :KCNB1
  
Synonyms : KCNB1 / potassium voltage-gated channel subfamily B member 1
  
Possible biological names infered from orthology : Q03717 / Q14721
  
Species: Gallus gallus
  
Chr. number: 20
Strand: -1
Band:
Gene start: 6716764
Gene end: 6815612
  
Corresponding Affymetrix probe sets: GgaAffx.2955.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000033591
NCBI entrez gene - 428146     See in Manteia.
RefSeq - XM_015296683
RefSeq - XM_425704
RefSeq - XM_015296684
RefSeq - XM_015296685
swissprot - E1BYX3
Ensembl - ENSGALG00000004758
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnb1ENSDARG00000060095Danio rerio
 KCNB1ENSG00000158445Homo sapiens
 Kcnb1ENSMUSG00000050556Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNB2 / potassium voltage-gated channel subfamily B member 2 / A6H8H5* / Q92953*ENSGALG0000003169366
KCNV1* / Q6PIU1* / Q8BZN2* / Potassium voltage-gated channel subfamily V member 1 * / potassium voltage-gated channel modifier subfamily V member 1*ENSGALG0000003144925
KCNS3 / potassium voltage-gated channel modifier subfamily S member 3 / Q8BQZ8* / Q9BQ31* / Potassium voltage-gated channel subfamily S member 3 *ENSGALG0000001647024
KCNS2 / potassium voltage-gated channel modifier subfamily S member 2 / O35174* / Q9ULS6* / Potassium voltage-gated channel subfamily S member 2 *ENSGALG0000004376422
KCNS1 / potassium voltage-gated channel modifier subfamily S member 1 / O35173* / Q96KK3* / Potassium voltage-gated channel subfamily S member 1 *ENSGALG0000000407422
KCNF1 / potassium voltage-gated channel modifier subfamily F member 1 / Q9H3M0*ENSGALG0000001644822
KCNG1 / potassium voltage-gated channel modifier subfamily G member 1 / A2BDX4* / Q9UIX4* / Potassium voltage-gated channel subfamily G member 1 *ENSGALG0000000798021
KCNV2 / potassium voltage-gated channel modifier subfamily V member 2 / Q8CFS6* / Q8TDN2* / Potassium voltage-gated channel subfamily V member 2 *ENSGALG0000001017320
KCNG4 / potassium voltage-gated channel modifier subfamily G member 4 / Q80XM3* / Q8TDN1* / Potassium voltage-gated channel subfamily G member 4 *ENSGALG0000000550220
KCNG2 / O73606 / Potassium voltage-gated channel subfamily G member 2 / Q9UJ96* / potassium voltage-gated channel modifier subfamily G member 2*ENSGALG0000003175420
ENSGALG0000002616119
KCNG3 / potassium voltage-gated channel modifier subfamily G member 3 / P59053* / Q8TAE7* / Potassium voltage-gated channel subfamily G member 3 *ENSGALG0000000991918


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR003131  Potassium channel tetramerisation-type BTB domain
 IPR003968  Potassium channel, voltage dependent, Kv
 IPR003973  Potassium channel, voltage dependent, Kv2
 IPR004350  Potassium channel, voltage dependent, Kv2.1
 IPR005821  Ion transport domain
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR027359  Voltage-dependent channel domain superfamily
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001508 action potential IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0046676 negative regulation of insulin secretion IEA
 biological_processGO:0051260 protein homooligomerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071333 cellular response to glucose stimulus IEA
 biological_processGO:0071805 potassium ion transmembrane transport IBA
 biological_processGO:0090314 positive regulation of protein targeting to membrane IEA
 biological_processGO:0098900 regulation of action potential IEA
 biological_processGO:1900454 positive regulation of long term synaptic depression IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0032809 neuronal cell body membrane IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IBA
 molecular_functionGO:0005251 delayed rectifier potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0044325 ion channel binding IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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