ENSGALG00000005527


Gallus gallus

Features
Gene ID: ENSGALG00000005527
  
Biological name :APPL1
  
Synonyms : adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 / APPL1
  
Possible biological names infered from orthology : DCC-interacting protein 13-alpha / Q8K3H0 / Q9UKG1
  
Species: Gallus gallus
  
Chr. number: 12
Strand: 1
Band:
Gene start: 8610054
Gene end: 8639123
  
Corresponding Affymetrix probe sets: GgaAffx.3464.1.S1_at (Chicken Array)   GgaAffx.3464.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000008851
NCBI entrez gene - 416002     See in Manteia.
RefSeq - XM_004944584
RefSeq - XM_414344
swissprot - E1C411
Ensembl - ENSGALG00000005527
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 appl1ENSDARG00000060734Danio rerio
 APPL1ENSG00000157500Homo sapiens
 Appl1ENSMUSG00000040760Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
APPL2 / adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 / Q8K3G9* / Q8NEU8* / DCC-interacting protein 13-beta *ENSGALG0000002712243


Protein motifs (from Interpro)
Interpro ID Name
 IPR001849  Pleckstrin homology domain
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR027267  AH/BAR domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008283 cell proliferation IEA
 biological_processGO:0008286 insulin receptor signaling pathway IEA
 biological_processGO:0046324 regulation of glucose import IEA
 biological_processGO:1903076 regulation of protein localization to plasma membrane IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0010008 endosome membrane IEA
 cellular_componentGO:0012506 vesicle membrane IEA
 cellular_componentGO:0016581 NuRD complex IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043422 protein kinase B binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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