ENSGALG00000005595


Gallus gallus

Features
Gene ID: ENSGALG00000005595
  
Biological name :HPS4
  
Synonyms : HPS4 / HPS4, biogenesis of lysosomal organelles complex 3 subunit 2
  
Possible biological names infered from orthology : Hermansky-Pudlak syndrome 4 protein homolog / Q99KG7 / Q9NQG7
  
Species: Gallus gallus
  
Chr. number: 15
Strand: -1
Band:
Gene start: 7194104
Gene end: 7204732
  
Corresponding Affymetrix probe sets: GgaAffx.3510.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000060933
Ensembl peptide - ENSGALP00000008962
NCBI entrez gene - 416907     See in Manteia.
RefSeq - XM_415198
RefSeq - XM_004945639
RefSeq - XM_015275489
swissprot - F1NQT3
swissprot - A0A1L1RQ63
Ensembl - ENSGALG00000005595
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hps4ENSDARG00000013795Danio rerio
 HPS4ENSG00000100099Homo sapiens
 Hps4ENSMUSG00000042328Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026091  Hermansky-Pudlak syndrome 4 protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006605 protein targeting IEA
 biological_processGO:0006996 organelle organization IEA
 biological_processGO:0007040 lysosome organization IEA
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0030318 melanocyte differentiation IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:1903232 melanosome assembly IEA
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031085 BLOC-3 complex IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0042827 platelet dense granule IEA
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0017137 Rab GTPase binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
RAB GEFs exchange GTP for GDP on RABs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000017419 HPS1 / HPS1, biogenesis of lysosomal organelles complex 3 subunit 1 / Q92902* / Mus musculus HPS1, biosis of lysosomal organelles complex 3 subunit 1 (Hps1), transcript variant 2, mRNA.*  / complex
 ENSGALG00000012300 RAB32 / RAB32, member RAS oncogene family / Q13637* / Q9CZE3*  / reaction
 ENSGALG00000028018 RAB38 / RAB38, member RAS oncogene family / P57729* / Q8QZZ8*  / reaction






 

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