ENSGALG00000006172


Gallus gallus

Features
Gene ID: ENSGALG00000006172
  
Biological name :ABCC8
  
Synonyms : ABCC8 / ATP binding cassette subfamily C member 8
  
Possible biological names infered from orthology : Q09428
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 11859274
Gene end: 11923796
  
Corresponding Affymetrix probe sets: GgaAffx.3854.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000009950
Ensembl peptide - ENSGALP00000053407
Ensembl peptide - ENSGALP00000051349
NCBI entrez gene - 423072     See in Manteia.
RefSeq - XM_421005
swissprot - E1C949
swissprot - A0A1D5PKP6
swissprot - A0A1D5PEY7
Ensembl - ENSGALG00000006172
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abcc8ENSDARG00000051879Danio rerio
 abcc8bENSDARG00000077007Danio rerio
 ABCC8ENSG00000006071Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ABCC9 / ATP binding cassette subfamily C member 9 / O60706* / P70170* / ATP-binding cassette, sub-family C (CFTR/MRP), member 9*ENSGALG0000001324470
ABCC1 / multidrug resistance-associated protein 1 / O35379* / P33527* / ATP binding cassette subfamily C member 1* / ATP-binding cassette, sub-family C (CFTR/MRP), member 1*ENSGALG0000000664631
ABCC3 / ATP binding cassette subfamily C member 3 / O15438*ENSGALG0000000752230
ABCC2 / ATP binding cassette subfamily C member 2 / Q8VI47* / Q92887* / Canalicular multispecific organic anion transporter 1 *ENSGALG0000000739529
ABCC6ENSGALG0000003815229
ENSGALG0000001567527
ABCC5 / ATP binding cassette subfamily C member 5 / O15440* / Q9R1X5* / Multidrug resistance-associated protein 5 *ENSGALG0000000836926
ABCC4 / ATP binding cassette subfamily C member 4 / O15439* / ATP-binding cassette, sub-family C (CFTR/MRP), member 4*ENSGALG0000001689625
CFTR / cystic fibrosis transmembrane conductance regulator / P13569* / P26361*ENSGALG0000003298621


Protein motifs (from Interpro)
Interpro ID Name
 IPR000388  Sulphonylurea receptor
 IPR000844  ATP-binding cassette subfamily C member 8
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0042493 response to drug IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IBA
 cellular_componentGO:0008282 inward rectifying potassium channel IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042383 sarcolemma IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005267 potassium channel activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008281 sulfonylurea receptor activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA
 molecular_functionGO:0044325 ion channel binding IEA


Pathways (from Reactome)
Pathway description
ATP sensitive Potassium channels
Regulation of insulin secretion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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