ENSDARG00000051879


Danio rerio

Features
Gene ID: ENSDARG00000051879
  
Biological name :abcc8
  
Synonyms : abcc8 / ATP-binding cassette, sub-family C (CFTR/MRP), member 8
  
Possible biological names infered from orthology : ATP binding cassette subfamily C member 8 / Q09428
  
Species: Danio rerio
  
Chr. number: 25
Strand: 1
Band:
Gene start: 22719852
Gene end: 22849186
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000082855
Ensembl peptide - ENSDARP00000124116
Ensembl peptide - ENSDARP00000124152
Ensembl peptide - ENSDARP00000124481
NCBI entrez gene - 553281     See in Manteia.
RefSeq - NM_001172647
RefSeq - XM_005170687
RefSeq - XM_009298033
RefSeq Peptide - NP_001166118
swissprot - F8W4W3
swissprot - F1QMZ9
swissprot - F8W367
swissprot - Q2HX27
ZFIN ID - ZDB-GENE-050517-22
Ensembl - ENSDARG00000051879
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ABCC8ENSGALG00000006172Gallus gallus
 ABCC8ENSG00000006071Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
abcc8b / ATP-binding cassette, sub-family C (CFTR/MRP), member 8b / ABCC8* / Q09428* / ATP binding cassette subfamily C member 8*ENSDARG0000007700774
abcc9 / ATP-binding cassette, sub-family C (CFTR/MRP), member 9 / O60706* / P70170* / ATP binding cassette subfamily C member 9*ENSDARG0000001598567
abcc1 / ATP-binding cassette, sub-family C (CFTR/MRP), member 1 / O35379* / P33527* / ATP binding cassette subfamily C member 1*ENSDARG0000010471930
abcc3 / ATP-binding cassette, sub-family C (CFTR/MRP), member 3 / O15438* / ATP binding cassette subfamily C member 3*ENSDARG0000009666230
abcc2 / ATP-binding cassette, sub-family C (CFTR/MRP), member 2 / Q92887* / Q8VI47* / ATP binding cassette subfamily C member 2* / Canalicular multispecific organic anion transporter 1 *ENSDARG0000001403129
abcc6b.2 / ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 2ENSDARG0000009490129
abcc6a / ATP-binding cassette, sub-family C (CFTR/MRP), member 6aENSDARG0000001675029
abcc10 / ATP-binding cassette, sub-family C (CFTR/MRP), member 10ENSDARG0000007798827
abcc12 / ATP-binding cassette, sub-family C (CFTR/MRP), member 12 / Q96J66* / Q80WJ6* / Q96J65* / ABCC11* / ATP binding cassette subfamily C member 12* / ATP binding cassette subfamily C me...ENSDARG0000001305025
si:ch211-221f10.2ENSDARG0000007654724
abcc4 / ATP-binding cassette, sub-family C (CFTR/MRP), member 4 / O15439* / ATP binding cassette subfamily C member 4*ENSDARG0000005895324
abcc5 / ATP-binding cassette, sub-family C (CFTR/MRP), member 5 / O15440* / Q9R1X5* / ATP binding cassette subfamily C member 5* / Multidrug resistance-associated protein 5 *ENSDARG0000006123324
abcc6b.1 / ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1ENSDARG0000010540320
cftr / Q1LX78 / cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) / P13569* / P26361* / cystic fibrosis transmembrane conductance regulator*ENSDARG0000004110719


Protein motifs (from Interpro)
Interpro ID Name
 IPR000388  Sulphonylurea receptor
 IPR000844  ATP-binding cassette subfamily C member 8
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006813 potassium ion transport IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0042493 response to drug IBA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IBA
 cellular_componentGO:0008282 inward rectifying potassium channel IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042383 sarcolemma IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005267 potassium channel activity IBA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008281 sulfonylurea receptor activity IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IBA


Pathways (from Reactome)
Pathway description
ATP sensitive Potassium channels
Regulation of insulin secretion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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