ENSDARG00000104719


Danio rerio

Features
Gene ID: ENSDARG00000104719
  
Biological name :abcc1
  
Synonyms : abcc1 / ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  
Possible biological names infered from orthology : ATP binding cassette subfamily C member 1 / O35379 / P33527
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 36713477
Gene end: 36743962
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000155836
Ensembl peptide - ENSDARP00000130505
Ensembl peptide - ENSDARP00000157625
NCBI entrez gene - 100002010     See in Manteia.
RefSeq - XM_001341859
swissprot - A0A0R4IC81
ZFIN ID - ZDB-GENE-050517-15
Ensembl - ENSDARG00000104719
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ABCC1ENSGALG00000006646Gallus gallus
 ABCC1ENSG00000103222Homo sapiens
 Abcc1ENSMUSG00000023088Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
abcc3 / ATP-binding cassette, sub-family C (CFTR/MRP), member 3 / O15438* / ATP binding cassette subfamily C member 3*ENSDARG0000009666259
abcc6b.2 / ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 2ENSDARG0000009490156
abcc6a / ATP-binding cassette, sub-family C (CFTR/MRP), member 6aENSDARG0000001675056
abcc2 / ATP-binding cassette, sub-family C (CFTR/MRP), member 2 / Q92887* / Q8VI47* / ATP binding cassette subfamily C member 2* / Canalicular multispecific organic anion transporter 1 *ENSDARG0000001403148
abcc6b.1 / ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1ENSDARG0000010540339
abcc10 / ATP-binding cassette, sub-family C (CFTR/MRP), member 10ENSDARG0000007798833
abcc8 / ATP-binding cassette, sub-family C (CFTR/MRP), member 8 / Q09428* / ATP binding cassette subfamily C member 8*ENSDARG0000005187932
abcc8b / ATP-binding cassette, sub-family C (CFTR/MRP), member 8b / ABCC8* / Q09428* / ATP binding cassette subfamily C member 8*ENSDARG0000007700731
abcc4 / ATP-binding cassette, sub-family C (CFTR/MRP), member 4 / O15439* / ATP binding cassette subfamily C member 4*ENSDARG0000005895331
abcc9 / ATP-binding cassette, sub-family C (CFTR/MRP), member 9 / O60706* / P70170* / ATP binding cassette subfamily C member 9*ENSDARG0000001598531
abcc5 / ATP-binding cassette, sub-family C (CFTR/MRP), member 5 / O15440* / Q9R1X5* / ATP binding cassette subfamily C member 5* / Multidrug resistance-associated protein 5 *ENSDARG0000006123330
abcc12 / ATP-binding cassette, sub-family C (CFTR/MRP), member 12 / Q96J66* / Q80WJ6* / Q96J65* / ABCC11* / ATP binding cassette subfamily C member 12* / ATP binding cassette subfamily C me...ENSDARG0000001305030
si:ch211-221f10.2ENSDARG0000007654730
cftr / Q1LX78 / cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) / P13569* / P26361* / cystic fibrosis transmembrane conductance regulator*ENSDARG0000004110724


Protein motifs (from Interpro)
Interpro ID Name
 IPR003439  ABC transporter-like
 IPR003593  AAA+ ATPase domain
 IPR005292  Multi drug resistance-associated protein
 IPR011527  ABC transporter type 1, transmembrane domain
 IPR017871  ABC transporter, conserved site
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071585 detoxification of cadmium ion IMP
 biological_processGO:0098754 detoxification IMP
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0022857 transmembrane transporter activity IEA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IEA


Pathways (from Reactome)
Pathway description
Cobalamin (Cbl, vitamin B12) transport and metabolism
Synthesis of Leukotrienes (LT) and Eoxins (EX)
ABC-family proteins mediated transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure increased amount , abnormal
anatomical structure decreased amount , abnormal
Show

 ZFA:0000114 heart heart edematous , exacerbated
Show

 ZFA:0001094 whole organism whole organism decreased life span , exacerbated
whole organism glutathione increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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