Manteia

ENSDARG00000061233

Danio rerio

Features

Gene ID:	ENSDARG00000061233

Biological name :	abcc5

Synonyms :	abcc5 / ATP-binding cassette, sub-family C (CFTR/MRP), member 5

Possible biological names infered from orthology :	ATP binding cassette subfamily C member 5 / Multidrug resistance-associated protein 5 / O15440 / Q9R1X5

Species:	Danio rerio

Chr. number:	18
Strand:	1
Band:
Gene start:	45792035
Gene end:	45851621

Corresponding Affymetrix probe sets:	Dr.6419.1.A1_at (Zebrafish Array)

Cross references:	Ensembl peptide - ENSDARP00000081504 Ensembl peptide - ENSDARP00000122401 NCBI entrez gene - 336147 See in Manteia. RefSeq - NM_001195613 RefSeq Peptide - NP_001182542 swissprot - E9QGZ9 swissprot - E7EYG0 ZFIN ID - ZDB-GENE-050517-17 Ensembl - ENSDARG00000061233

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
ABCC5	ENSGALG00000008369	Gallus gallus
ABCC5	ENSG00000114770	Homo sapiens
Abcc5	ENSMUSG00000022822	Mus musculus

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
si:ch211-221f10.2	ENSDARG00000076547	57
abcc12 / ATP-binding cassette, sub-family C (CFTR/MRP), member 12 / Q96J66* / Q80WJ6* / Q96J65* / ABCC11* / ATP binding cassette subfamily C member 12* / ATP binding cassette subfamily C me...	ENSDARG00000013050	43
abcc3 / ATP-binding cassette, sub-family C (CFTR/MRP), member 3 / O15438* / ATP binding cassette subfamily C member 3*	ENSDARG00000096662	33
abcc2 / ATP-binding cassette, sub-family C (CFTR/MRP), member 2 / Q92887* / Q8VI47* / ATP binding cassette subfamily C member 2* / Canalicular multispecific organic anion transporter 1 *	ENSDARG00000014031	33
abcc1 / ATP-binding cassette, sub-family C (CFTR/MRP), member 1 / O35379* / P33527* / ATP binding cassette subfamily C member 1*	ENSDARG00000104719	32
abcc4 / ATP-binding cassette, sub-family C (CFTR/MRP), member 4 / O15439* / ATP binding cassette subfamily C member 4*	ENSDARG00000058953	31
abcc6b.2 / ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 2	ENSDARG00000094901	30
abcc6a / ATP-binding cassette, sub-family C (CFTR/MRP), member 6a	ENSDARG00000016750	30
abcc10 / ATP-binding cassette, sub-family C (CFTR/MRP), member 10	ENSDARG00000077988	29
abcc9 / ATP-binding cassette, sub-family C (CFTR/MRP), member 9 / O60706* / P70170* / ATP binding cassette subfamily C member 9*	ENSDARG00000015985	28
abcc8b / ATP-binding cassette, sub-family C (CFTR/MRP), member 8b / ABCC8* / Q09428* / ATP binding cassette subfamily C member 8*	ENSDARG00000077007	27
abcc8 / ATP-binding cassette, sub-family C (CFTR/MRP), member 8 / Q09428* / ATP binding cassette subfamily C member 8*	ENSDARG00000051879	27
abcc6b.1 / ATP-binding cassette, sub-family C (CFTR/MRP), member 6b, tandem duplicate 1	ENSDARG00000105403	24
cftr / Q1LX78 / cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) / P13569* / P26361* / cystic fibrosis transmembrane conductance regulator*	ENSDARG00000041107	23

Protein motifs (from Interpro)

Interpro ID	Name
IPR003439	ABC transporter-like
IPR003593	AAA+ ATPase domain
IPR011527	ABC transporter type 1, transmembrane domain
IPR017871	ABC transporter, conserved site
IPR027417	P-loop containing nucleoside triphosphate hydrolase
IPR030238	Multidrug resistance-associated protein 5

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0015711	organic anion transport	IEA
biological_process	GO:0030218	erythrocyte differentiation	IMP
biological_process	GO:0035351	heme transmembrane transport	IMP
biological_process	GO:0055085	transmembrane transport	IEA
cellular_component	GO:0005887	integral component of plasma membrane	IBA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0008514	organic anion transmembrane transporter activity	IEA
molecular_function	GO:0016887	ATPase activity	IEA
molecular_function	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IBA

Pathways (from Reactome)

Pathway description

Hyaluronan biosynthesis and export

ABC-family proteins mediated transport

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
ZFA:0005023	hematopoietic system	hematopoietic system has fewer parts of type nucleate erythrocyte , abnormal	Show

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr